Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 8/20 | 0.43 |
| ▸ | HTR2A | P28223 | 8/20 | 0.43 |
| ▸ | HTR1A | P08908 | 8/20 | 0.43 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.38 |
| ▸ | HTR7 | P34969 | 7/20 | 0.38 |
| ▸ | HTR6 | P50406 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7686993 | 0.92 | DRD2 (0.46) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL7686952 | 0.83 | ALDH1A1 (0.51) | DRD2ADRA1DADRA1AADRA1B | |
| SCHEMBL7687016 | 0.81 | HTR1A (0.53) | DRD2HTR2AHTR1AADRA1DADRA1A | |
| SCHEMBL7685522 | 0.81 | HTR7 (0.48) | DRD2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7682473 | 0.73 | HTR1A (0.54) | DRD2HTR2AHTR1AHTR7 | |
| SCHEMBL7684659 | 0.73 | MEN1 (0.54) | DRD2HTR1AADRA1AADRA1B | |
| SCHEMBL2056184 | 0.72 | HTR1A (0.51) | DRD2HTR2AHTR1AADRA1DADRA1A | |
| SCHEMBL7686048 | 0.70 | HTR7 (0.42) | DRD2HTR2AHTR1AHTR7HTR6 | |
| SCHEMBL7675521 | 0.70 | HRH4 (0.54) | DRD2HTR1AADRA1DADRA1AADRA1B | |
| SCHEMBL7683751 | 0.70 | HTR1A (0.57) | DRD2HTR2AHTR1AADRA1DADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346622-B1 | ENANTIOMORPHS AND ISOMERS | ABBOTT LABORATORIES | 2002-02-12 | — | — | US | disclosed |