Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | DRD2 | P14416 | 2/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7687016 | 0.85 | HTR1A (0.53) | DRD2ADRA1ADRD3ADRA1DADRA1B | |
| SCHEMBL7683519 | 0.83 | DRD2 (0.43) | DRD2ADRA1AADRA1DADRA1B | |
| SCHEMBL7685522 | 0.83 | HTR7 (0.48) | DRD2ADRA1ADRD3ADRA1DADRA1B | |
| SCHEMBL7684659 | 0.78 | MEN1 (0.54) | ALDH1A1MEN1KMT2ATSHRMAPK1 | |
| SCHEMBL7686993 | 0.78 | DRD2 (0.46) | DRD2DRD3 | |
| SCHEMBL7682473 | 0.76 | HTR1A (0.54) | MEN1KMT2AMAPK1DRD2MAPT | |
| SCHEMBL7686048 | 0.73 | HTR7 (0.42) | DRD2LMNAKDM4E | |
| SCHEMBL7675521 | 0.73 | HRH4 (0.54) | ALDH1A1MAPK1DRD2ADRA1ADRD3 | |
| SCHEMBL7683751 | 0.72 | HTR1A (0.57) | ALDH1A1DRD2ADRA1ADRD3ADRA1D | |
| SCHEMBL7677803 | 0.72 | HTR7 (0.51) | DRD2ADRA1ADRD3ADRA1DADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6346622-B1 | ENANTIOMORPHS AND ISOMERS | ABBOTT LABORATORIES | 2002-02-12 | — | — | US | disclosed |