Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 1/20 | 0.43 |
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 3/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 2/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.39 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700930 | 0.89 | MAPT (0.46) | ADKCFDKDM4EMAPK1HTT | |
| SCHEMBL7700864 | 0.88 | CFD (0.44) | ADKCFDKDM4EHTTSRC | |
| SCHEMBL7700385 | 0.87 | ADORA2A (0.52) | ADKCFDKDM4EMAPK1HTT | |
| SCHEMBL7701968 | 0.87 | RIPK2 (0.45) | ADKCFDSRCRIPK2PI4KB | |
| SCHEMBL7696329 | 0.87 | ADK (0.41) | ADKCFDKDM4EMAPK1HTT | |
| SCHEMBL7703250 | 0.86 | CFD (0.42) | ADKCFDKDM4EMAPK1HTT | |
| SCHEMBL7701985 | 0.82 | SLC29A1 (0.44) | ADKCFDADORA2APIK3CDPIK3CA | |
| SCHEMBL7702542 | 0.81 | CFD (0.43) | ADKCFDKDM4EMAPK1HTT | |
| SCHEMBL18520393 | 0.80 | ADK (0.49) | ADKCFDSRCLRRK2RET | |
| SCHEMBL19780034 | 0.79 | KLKB1 (0.52) | ADKCFDRET |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |