Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | CFD | P00746 | 1/20 | 0.43 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 4/20 | 0.41 |
| ▸ | KDR | P35968 | 3/20 | 0.41 |
| ▸ | LCK | P06239 | 2/20 | 0.41 |
| ▸ | TEK | Q02763 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 2/20 | 0.40 |
| ▸ | PI4KA | P42356 | 2/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.39 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | NSD2 | O96028 | 2/20 | 0.39 |
| ▸ | NSD3 | Q9BZ95 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700864 | 0.89 | CFD (0.44) | CFDADKMEN1SRCKDR | |
| SCHEMBL7698564 | 0.89 | ADK (0.43) | CFDADKCYP1A2MAPK1SRC | |
| SCHEMBL7700385 | 0.88 | ADORA2A (0.52) | CFDADKMAPK1MEN1KMT2A | |
| SCHEMBL7701968 | 0.85 | RIPK2 (0.45) | CFDADKSRCKDRLCK | |
| SCHEMBL7696329 | 0.85 | ADK (0.41) | CFDADKCYP1A2MAPK1MEN1 | |
| SCHEMBL19780034 | 0.85 | KLKB1 (0.52) | MAPTCFDADKRET | |
| SCHEMBL7701985 | 0.83 | SLC29A1 (0.44) | CFDADKMEN1KMT2AADORA2A | |
| SCHEMBL7703250 | 0.80 | CFD (0.42) | CFDADKMAPK1TDP1SRC | |
| SCHEMBL18520393 | 0.78 | ADK (0.49) | CFDADKSRCKDRLCK | |
| SCHEMBL7702542 | 0.77 | CFD (0.43) | CFDADKMAPK1SRCKDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |