Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.44 |
| ▸ | ADK | P55263 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | RET | P07949 | 2/20 | 0.39 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 2/20 | 0.39 |
| ▸ | HCK | P08631 | 2/20 | 0.39 |
| ▸ | SRC | P12931 | 2/20 | 0.39 |
| ▸ | KDR | P35968 | 2/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.39 |
| ▸ | MTOR | P42345 | 2/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.39 |
| ▸ | EPHB4 | P54760 | 2/20 | 0.39 |
| ▸ | PRKDC | P78527 | 2/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7700930 | 0.89 | MAPT (0.46) | CFDADKRETRIPK2PIK3CD | |
| SCHEMBL7695185 | 0.88 | ADORA2A (0.41) | CFDADKRETPIK3CDABL1 | |
| SCHEMBL7698564 | 0.88 | ADK (0.43) | CFDADKRETRIPK2PIK3CD | |
| SCHEMBL7700385 | 0.87 | ADORA2A (0.52) | CFDADKRETPIK3CDABL1 | |
| SCHEMBL7696329 | 0.84 | ADK (0.41) | CFDADKRETPIK3CDABL1 | |
| SCHEMBL7701968 | 0.84 | RIPK2 (0.45) | CFDADKRIPK2PIK3CDABL1 | |
| SCHEMBL7701985 | 0.82 | SLC29A1 (0.44) | CFDADKPIK3CDPIK3CAPIK3CB | |
| SCHEMBL19780034 | 0.79 | KLKB1 (0.52) | CFDADKRET | |
| SCHEMBL7703250 | 0.79 | CFD (0.42) | CFDADKRETRIPK2PIK3CD | |
| SCHEMBL17406909 | 0.79 | RPS6KB1 (0.41) | P2RX7RETRIPK2SRCADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |