Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CFD | P00746 | 1/20 | 0.42 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | RET | P07949 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.41 |
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | SRC | P12931 | 4/20 | 0.40 |
| ▸ | ABL1 | P00519 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | HCK | P08631 | 1/20 | 0.40 |
| ▸ | KDR | P35968 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7698564 | 0.86 | ADK (0.43) | CFDADORA2AKDM4ETSHRMAPK1 | |
| SCHEMBL7700385 | 0.86 | ADORA2A (0.52) | CFDADORA2AKDM4ETSHRMAPK1 | |
| SCHEMBL7700961 | 0.82 | PAX8 (0.44) | CFDADORA2ARETLMNAALDH1A1 | |
| SCHEMBL7700930 | 0.80 | MAPT (0.46) | CFDADORA2AKDM4ETSHRMAPK1 | |
| SCHEMBL7702542 | 0.79 | CFD (0.43) | CFDADORA2AKDM4ETSHRMAPK1 | |
| SCHEMBL7700864 | 0.79 | CFD (0.44) | CFDADORA2AKDM4EHTTLRRK2 | |
| SCHEMBL7695714 | 0.79 | ADRA1D (0.51) | CFDKDM4ETSHRMAPK1HTT | |
| SCHEMBL8991101 | 0.79 | RIPK2 (0.42) | ADORA2AKDM4ETSHRMAPK1HTT | |
| SCHEMBL7697684 | 0.79 | ADRA1D (0.41) | ADORA2AKDM4ETSHRMAPK1HTT | |
| SCHEMBL7701968 | 0.78 | RIPK2 (0.45) | CFDRIPK2ADKSRCABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6342501-B1 | VIRICIDES | THE REGENTS OF THE UNIVERSITY OF MICHIGAN | 2002-01-29 | — | — | US | disclosed |
| US-5543413-A | VIRAL ACTIVITY AGAINST HUMAN CYTOMEGALOVIRUS AND HERPES SIMPLEX VIRUS | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 1996-08-06 | — | — | US | disclosed |