Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.52 |
| ▸ | CES1 | P23141 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.47 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.47 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.47 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.47 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13622409 | 0.84 | LMNA (0.56) | ALDH1A1MAPK1SMN1; SMN2HTTCES2 | |
| SCHEMBL14982190 | 0.84 | LMNA (0.49) | ALDH1A1MAPK1SMN1; SMN2HTTCES2 | |
| SCHEMBL5565698 | 0.83 | HSD17B3 (0.57) | ALDH1A1MAPK1SMN1; SMN2HTTCES2 | |
| SCHEMBL5300509 | 0.83 | ATM (0.47) | ALDH1A1MAPK1SMN1; SMN2HTTMEN1 | |
| SCHEMBL14357333 | 0.83 | HPGD (0.50) | ALDH1A1MAPK1SMN1; SMN2HTTMEN1 | |
| SCHEMBL7049792 | 0.83 | ALDH1A1 (0.50) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL5186624 | 0.83 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL3899593 | 0.83 | HTT (0.52) | ALDH1A1SMN1; SMN2HTTCES2CES1 | |
| SCHEMBL7049515 | 0.82 | MAPT (0.66) | ALDH1A1SMN1; SMN2HTTMEN1KMT2A | |
| SCHEMBL770793 | 0.82 | CHRNA1 (0.47) | ALDH1A1MAPK1SMN1; SMN2HTTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220324865-A1 | SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES | BAYER PHARMA AKTIENGESELLSCHAFT (DE) | 2022-10-13 | — | — | US | disclosed |
| WO-2022104049-A1 | SYNTHESIS OF ARYL 1-(METHOXYMETHYL) VINYL KETONES AND THEIR USE AS INHIBITORS OF MILD STEEL CORROSION | SAUDI ARABIAN OIL COMPANY (SA) | 2022-05-19 | — | — | WO | disclosed |
| US-20220145179-A1 | SYNTHESIS OF ARYL 1-(METHOXYMETHYL) VINYL KETONES AND THEIR USE AS INHIBITORS OF MILD STEEL CORROSION | SAUDI ARABIAN OIL COMPANY (SA) | 2022-05-12 | — | — | US | disclosed |
| CN-112010881-B | Alkenyl boron compound and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2021-09-03 | — | — | CN | disclosed |
| EP-3793559-A1 | SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES | Bayer Aktiengesellschaft (DE) | 2021-03-24 | — | — | EP | disclosed |
| CN-112469412-A | Substituted dihydropyrazolopyrazine carboxamide derivatives | 拜耳公司 | 2021-03-09 | — | — | CN | disclosed |
| CN-112010881-A | Alkenyl boron compound and preparation method and application thereof | 中国科学院兰州化学物理研究所 | 2020-12-01 | — | — | CN | disclosed |
| US-9988350-B2 | Aniline derivative, pharmaceutical composition containing same, and use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2018-06-05 | — | — | US | disclosed |
| US-20170320821-A1 | NOVEL ANILINE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2017-11-09 | — | — | US | disclosed |
| US-9718771-B2 | Aniline derivative, pharmaceutical composition containing same, and use thereof | KISSEI PHARMACEUTICAL CO., LTD. (JP) | 2017-08-01 | — | — | US | disclosed |
| US-5057535-A | Muscle relaxants | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1991-10-15 | — | — | US | disclosed |
| EP-0328669-A1 | CHALCONE DERIVATIVE COMPOUNDS | NIPPON OIL AND FATS COMPANY, LIMITED (JP) | 1989-08-23 | — | — | EP | disclosed |
| EP-0200942-A2 | New derivatives of an aminoketone | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1986-11-12 | — | — | EP | disclosed |
| US-4563454-A | ASTHMA, RHINITIS, DERMATITIS | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1986-01-07 | — | — | US | disclosed |
| EP-0004000-B1 | NEW PROPANONE DERIVATIVES, PROCESS FOR PRODUCING THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE DERIVATIVES AS ACTIVE INGREDIENTS | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1984-11-28 | — | — | EP | disclosed |
| US-4277474-A | DERMATITIS, RHINITIS, ASTHMA | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1981-07-07 | — | — | US | disclosed |
| US-4184874-A | Photosensitive composition containing chelate compound | FUJI PHOTO FILM CO., LTD. (JP) | 1980-01-22 | — | — | US | disclosed |
| EP-0004000-A1 | New propanone derivatives, process for producing thereof and pharmaceutical compositions containing these derivatives as active ingredients | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1979-09-19 | — | — | EP | disclosed |
| US-3975373-A | CYCLOPENTANONE HELVETICOSIDE | JOHANN A. WULFING FABRIK PHARMAZEUTISCHER PRAPARATE (DT) | 1976-08-17 | — | — | US | disclosed |
| US-3951946-A | Cardioglycoside derivatives of the strophanthidin type, a process for their manufacture and medicinal preparations containing these compounds | JOHANN A. WULFING FABRIK PHARMAZEUTISCHER PRAPARATE (DT) | 1976-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220324865-A1 | SUBSTITUTED DIHYDROPYRAZOLO PYRAZINE CARBOXAMIDE DERIVATIVES | QDPR, SIRT5, PDXK | ALDH1A1 767/4885MAPK1 2129/4885SMN1; SMN2 3131/4885 |
| US-20220145179-A1 | SYNTHESIS OF ARYL 1-(METHOXYMETHYL) VINYL KETONES AND THEIR USE AS INHIBITORS OF MILD STEEL CORROSION | PAH, CYP2F1, ADH1C | ALDH1A1 15/4885MAPK1 569/4885SMN1; SMN2 3579/4885 |
| US-20170320821-A1 | NOVEL ANILINE DERIVATIVE, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | S1PR3, S1PR1, S1PR2 | ALDH1A1 2780/4885MAPK1 1870/4885SMN1; SMN2 3649/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.