SCHEMBL7702939

SCHEMBL7702939

Cc1ccc([I+]c2ccccc2)cc1.O=S(=O)([O-])C(F)(F)C(F)(F)C(F)(F)C(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GPR3 P46089 1/20 0.35
TLR9 Q9NR96 1/20 0.35
MMP2 P08253 5/20 0.35
NPSR1 Q6W5P4 1/20 0.35
CA1 P00915 8/20 0.34
CA2 P00918 8/20 0.34
MMP1 P03956 4/20 0.34
MMP9 P14780 4/20 0.34
MMP8 P22894 4/20 0.34
MMP13 P45452 4/20 0.34
CA12 O43570 3/20 0.34
CA9 Q16790 3/20 0.34
CYP3A4 P08684 2/20 0.34
CYP1A2 P05177 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
CYP2C19 P33261 1/20 0.33
KCNH2 Q12809 1/20 0.33
HTT P42858 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Toliodium SCHEMBL2895493 0.94 TLR9 (0.39) GPR3TLR9MMP2CA1CA2
Toliodium SCHEMBL2897584 0.93 CA2 (0.38) TLR9MMP2CA1CA2MMP1
SCHEMBL51422 0.91 CA2 (0.38) GPR3MMP2CA1CA2MMP1
SCHEMBL59303 0.90 CA2 (0.40) GPR3MMP2CA1CA2MMP1
SCHEMBL213386 0.90 CA2 (0.40) GPR3MMP2CA1CA2MMP1
SCHEMBL4219795 0.89 ACHE (0.37) TLR9CA1CA2CA9L3MBTL1
Trifluoromethanesulfonic Acid SCHEMBL12613417 0.88 GPR3 (0.40) GPR3MMP2CA1CA2MMP1
SCHEMBL1805421 0.87 CA2 (0.34) MMP2CA1CA2MMP1MMP9
SCHEMBL7708260 0.86 HSD11B1 (0.38) MMP2CA1CA2MMP1MMP9
SCHEMBL3284031 0.86 CA2 (0.35) MMP2CA1CA2MMP1MMP9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6358665-B1 ONIUM SALT PRECURSOR FOR GENERATING FLUOROALKYLSULFONATE CLARIANT INTERNATIONAL LTD. (CH) 2002-03-19 US disclosed
EP-1033624-A1 RADIATION-SENSITIVE COMPOSITION OF CHEMICAL AMPLIFICATION TYPE Clariant International Ltd. (CH) 2000-09-06 EP disclosed