Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 3/20 | 0.56 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.56 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | TDO2 | P48775 | 1/20 | 0.41 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.38 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.37 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.37 |
| ▸ | HHAT | Q5VTY9 | 2/20 | 0.37 |
| ▸ | KIF11 | P52732 | 1/20 | 0.36 |
| ▸ | EDNRA | P25101 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | XIAP | P98170 | 1/20 | 0.36 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1176599 | 0.80 | HTR6 (0.48) | MTNR1AMTNR1BIDO1TDO2KIF11 | |
| SCHEMBL7413568 | 0.75 | LTB4R (0.43) | IDO1TDO2KIF11EDNRAALPI | |
| SCHEMBL7698344 | 0.75 | IDO1 (0.40) | MTNR1AMTNR1BIDO1TDO2KIF11 | |
| SCHEMBL7703390 | 0.74 | MTNR1A (0.54) | MTNR1AMTNR1BSIGMAR1SLC6A9IDO1 | |
| SCHEMBL9510931 | 0.74 | MTNR1A (0.63) | MTNR1AMTNR1BSIGMAR1SLC6A9CYP11B2 | |
| SCHEMBL12591535 | 0.74 | SLC6A9 (0.71) | MTNR1AMTNR1BSIGMAR1SLC6A9CYP11B2 | |
| Hydrochloric Acid SCHEMBL7706074 | 0.73 | SLC6A9 (0.70) | MTNR1AMTNR1BSIGMAR1SLC6A9CYP11B2 | |
| Hydrochloric Acid SCHEMBL7706012 | 0.73 | MTNR1A (0.65) | MTNR1AMTNR1BSIGMAR1SLC6A9CYP11B2 | |
| SCHEMBL7576271 | 0.71 | SIGMAR1 (0.54) | MTNR1AMTNR1BSIGMAR1CYP11B2EDNRA | |
| Aspartic Acid SCHEMBL17727762 | 0.70 | FFAR1 (0.41) | MTNR1AMTNR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1100769-B1 | AMINOMETHYLCARBOXYLIC ACID DERIVATIVES | AKZO NOBEL NV (NL) | 2002-12-04 | — | — | EP | disclosed |
| US-6410592-B1 | THERAPY FOR CENTRAL NERVOUS SYSTEM DISORDERS, PSYCHOLOGICAL DISORDERS | AKZO NOBEL N.V. (NL) | 2002-06-25 | — | — | US | disclosed |