Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 8/20 | 0.50 |
| ▸ | ACE | P12821 | 1/20 | 0.45 |
| ▸ | TACR1 | P25103 | 8/20 | 0.44 |
| ▸ | ERAP2 | Q6P179 | 6/20 | 0.44 |
| ▸ | ERAP1 | Q9NZ08 | 4/20 | 0.44 |
| ▸ | GPR132 | Q9UNW8 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7511099 | 0.81 | ACE (0.64) | LNPEPACETACR1GPR132 | |
| SCHEMBL7553966 | 0.79 | GPR132 (0.58) | LNPEPACEERAP2ERAP1GPR132 | |
| SCHEMBL7703848 | 0.78 | GPR132 (0.63) | LNPEPACETACR1ERAP2GPR132 | |
| SCHEMBL7523142 | 0.75 | ACE (0.50) | LNPEPACETACR1ERAP2ERAP1 | |
| SCHEMBL7709356 | 0.72 | ACE (0.50) | LNPEPACEERAP2ERAP1 | |
| SCHEMBL7686560 | 0.72 | ITGA4 (0.48) | LNPEPACETACR1ERAP2ERAP1 | |
| SCHEMBL8408864 | 0.72 | ACE (0.64) | LNPEPACETACR1GPR132 | |
| SCHEMBL8412255 | 0.72 | ACE (0.57) | LNPEPACETACR1ERAP1GPR132 | |
| SCHEMBL7522184 | 0.71 | ATM (0.50) | LNPEPACEERAP2 | |
| SCHEMBL8412259 | 0.71 | ACE (0.56) | LNPEPACETACR1ERAP2ERAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6362165-B1 | Hydroxyphenyl derivatives with HIV integrase inhibitory properties | PHARMACOR INC. (CA) | 2002-03-26 | — | — | US | disclosed |