Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.40 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | FEN1 | P39748 | 1/20 | 0.36 |
| ▸ | CEL | P19835 | 1/20 | 0.36 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23854308 | 0.86 | ADRA2A (0.41) | HTR2CADRA2AADRA2BADRA2CSLC6A3 | |
| SCHEMBL20036789 | 0.84 | ALDH1A1 (0.41) | HTR2CADRA2AADRA2BADRA2CSLC6A3 | |
| SCHEMBL20676750 | 0.81 | FEN1 (0.39) | HTR2CADRA2AADRA2BADRA2CSLC6A3 | |
| SCHEMBL30218222 | 0.81 | ALDH1A1 (0.48) | HTR2CALDH1A1FEN1PTGDR2TRPA1 | |
| SCHEMBL8954630 | 0.81 | ALDH1A1 (0.48) | HTR2CALDH1A1FEN1PTGDR2TRPA1 | |
| SCHEMBL11709395 | 0.81 | ALDH1A1 (0.38) | HTR2CADRA2AADRA2BADRA2CSLC6A3 | |
| SCHEMBL673222 | 0.81 | ALDH1A1 (0.48) | HTR2CALDH1A1FEN1PTGDR2TRPA1 | |
| SCHEMBL6390262 | 0.79 | HTR2C (0.50) | HTR2CALDH1A1CELKDM4EMEN1 | |
| Methane SCHEMBL9104929 | 0.79 | ALDH1A1 (0.46) | HTR2CALDH1A1FEN1PTGDR2TRPA1 | |
| SCHEMBL466853 | 0.78 | ALDH1A1 (0.50) | HTR2CALDH1A1FEN1KDM4ETRPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616429-B1 | METHOD FOR PRODUCING AROMATIC AMINES | BASF SE (DE) | 2015-08-05 | — | — | EP | disclosed |
| CN-103209953-B | Method for producing aromatic amines | BASF SE | 2015-05-27 | — | — | CN | disclosed |
| EP-2616429-A1 | METHOD FOR PRODUCING AROMATIC AMINES | BASF SE (DE) | 2013-07-24 | — | — | EP | disclosed |
| CN-103209953-A | Method for producing aromatic amines | BASF SE | 2013-07-17 | — | — | CN | disclosed |
| US-20120071692-A1 | PROCESS FOR THE PREPARATION OF AROMATIC AMINES | BASF SE (DE) | 2012-03-22 | — | — | US | disclosed |
| WO-2012034933-A1 | METHOD FOR PRODUCING AROMATIC AMINES | BASF SE (DE) | 2012-03-22 | — | — | WO | disclosed |
| CN-101208290-B | Method for the continuous production of an amine | BASF AG | 2011-01-19 | — | — | CN | disclosed |
| US-7767855-B2 | Method for the continuous production of an amine | BASF SE (DE) | 2010-08-03 | — | — | US | disclosed |
| EP-1899291-B1 | METHOD FOR THE CONTINUOUS PRODUCTION OF AN AMINE | BASF SE (DE) | 2009-03-18 | — | — | EP | disclosed |
| US-20080200726-A1 | Method For the Continuous Production of an Amine | BASF AKTIENGESELLSCHAFT (DE) | 2008-08-21 | — | — | US | disclosed |
| CN-101208290-A | Method for the continuous production of an amine | BASF AG (DE) | 2008-06-25 | — | — | CN | disclosed |
| EP-0701995-B1 | Process for the preparation of aromatic amines from aliphatic amines and the preparation of the latter by amino-hydrogenation | BASF AG (DE) | 1998-12-23 | — | — | EP | disclosed |
| US-5663438-A | DEHYDROGENATION CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1997-09-02 | — | — | US | disclosed |
| EP-0701995-A2 | Process for the preparation of aromatic amines from aliphatic amines and their preparation by hydrogenation in the presence of amines | BASF AKTIENGESELLSCHAFT (DE) | 1996-03-20 | — | — | EP | disclosed |
| EP-0167996-A1 | Process for the preparation of cyclic amines substituted on the ring | BASF Aktiengesellschaft (DE) | 1986-01-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071692-A1 | PROCESS FOR THE PREPARATION OF AROMATIC AMINES | ADH1A, ADH5, ADH1C | HTR2C 1506/4885ADRA2A 91/4885ADRA2B 426/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.