Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MITF | O75030 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | GFER | P55789 | 1/20 | 0.40 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.39 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7717232 | 0.80 | LMNA (0.48) | ALDH1A1MITFHTTRAB9AGFER | |
| SCHEMBL6862148 | 0.79 | ALDH1A1 (0.58) | ALDH1A1MITFHTTRAB9AGFER | |
| SCHEMBL7718149 | 0.79 | LMNA (0.46) | ALDH1A1MITFHTTRAB9AGFER | |
| SCHEMBL7718666 | 0.78 | SLC6A4 (0.49) | OPRK1ALDH1A1MITFHTTRAB9A | |
| SCHEMBL7718161 | 0.77 | ALDH1A1 (0.60) | ALDH1A1MITFHTTRAB9AGFER | |
| SCHEMBL7718661 | 0.76 | LMNA (0.53) | OPRK1ALDH1A1MITFHTTRAB9A | |
| SCHEMBL7718210 | 0.76 | KMT2A (0.50) | ALDH1A1MITFHTTRAB9AGFER | |
| SCHEMBL7719730 | 0.72 | GSK3B (0.43) | OPRK1ALDH1A1MITFHTTRAB9A | |
| SCHEMBL7718155 | 0.72 | ALDH1A1 (0.54) | ALDH1A1MITFHTTRAB9AGFER | |
| SCHEMBL12123644 | 0.71 | ALDH1A1 (0.57) | ALDH1A1GFERCYP2C9MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6384063-B1 | Compound having effect of promoting neuron differentiation | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2002-05-07 | — | — | US | disclosed |
| EP-0999204-A1 | NOVEL COMPOUND HAVING EFFECT OF PROMOTING NEURON DIFFERENTIATION | Nippon Kayaku Kabushiki Kaisha (JP) | 2000-05-10 | — | — | EP | disclosed |