Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CASP7 | P55210 | 1/20 | 0.35 |
| ▸ | HBB | P68871 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720013 | 0.87 | LMNA (0.39) | NAAALMNAPAX8HTTTSHR | |
| SCHEMBL7725838 | 0.80 | GAA (0.44) | NAAALMNAPAX8HTTTSHR | |
| SCHEMBL7720015 | 0.79 | HPGD (0.43) | NAAALMNAPAX8TSHRPOLB | |
| SCHEMBL7730016 | 0.77 | ADRB2 (0.39) | LMNATSHRSMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL7720001 | 0.75 | LMNA (0.48) | NAAALMNAPAX8HTTTSHR | |
| SCHEMBL7724598 | 0.75 | MGLL (0.49) | NAAALMNAPAX8HTTTSHR | |
| SCHEMBL7724600 | 0.74 | CYP2C9 (0.51) | NAAALMNAPAX8POLBKMT2A | |
| SCHEMBL7724420 | 0.73 | EGFR (0.44) | NAAALMNAPAX8HTTTSHR | |
| SCHEMBL7724416 | 0.73 | EGFR (0.44) | NAAALMNAPAX8HTTTSHR | |
| SCHEMBL7719994 | 0.72 | ACHE (0.38) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403818-B1 | ONE POT PROCESS STARTING FROM CARBONYL COMPOUND, ALCOHOL, THIOL OR AMINE, AND PROTECTED HYDROXYDICYANO COMPOUND | EISAI CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |