Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.50 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.47 |
| ▸ | KDM5B | Q9UGL1 | 9/20 | 0.43 |
| ▸ | KDM5A | P29375 | 7/20 | 0.43 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | KDM4C | Q9H3R0 | 4/20 | 0.39 |
| ▸ | DHODH | Q02127 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | KDM4A | O75164 | 2/20 | 0.39 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9224289 | 0.88 | KDM5B (0.50) | KDM5BKDM5AKEAP1ALDH1A1KDM4E | |
| SCHEMBL14347043 | 0.86 | DDAH1 (0.46) | TNKS2DDAH1 | |
| SCHEMBL9589018 | 0.86 | KDM5B (0.47) | KDM5BKDM5AKEAP1ALDH1A1KDM4E | |
| SCHEMBL14347065 | 0.84 | DDAH1 (0.44) | TNKS2DDAH1KEAP1ALDH1A1KDM4E | |
| SCHEMBL7721019 | 0.84 | DDAH1 (0.44) | TNKS2DDAH1KDM5AALDH1A1KDM4E | |
| SCHEMBL29893727 | 0.84 | DHODH (0.42) | KDM5BKDM5AKEAP1ALDH1A1KDM4E | |
| SCHEMBL14347064 | 0.84 | DDAH1 (0.44) | TNKS2DDAH1ALDH1A1KDM4ERAB9A | |
| SCHEMBL1553897 | 0.82 | GAA (0.54) | KDM5BKDM5AALDH1A1KDM4EKDM4C | |
| Hydrochloric Acid SCHEMBL8569715 | 0.81 | GAA (0.53) | KDM5BKDM5AALDH1A1KDM4EKDM4C | |
| SCHEMBL6948961 | 0.81 | RAB9A (0.55) | KDM5BKDM5AALDH1A1RAB9AKDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10729738-B2 | Hindered disulfide drug conjugates | GENENTECH, INC. (US) | 2020-08-04 | — | — | US | disclosed |
| US-20170112891-A1 | HINDERED DISULFIDE DRUG CONJUGATES | GENENTECH INC (US) | 2017-04-27 | — | — | US | disclosed |
| WO-2017064675-A1 | HINDERED DISULFIDE DRUG CONJUGATES | GENENTECH, INC. (US) | 2017-04-20 | — | — | WO | disclosed |
| US-8426401-B2 | Azetidinyl diamides as monoacylglycerol lipase inhibitors | JANSSEN PHARMACEUTICA, NV | 2013-04-23 | — | — | US | disclosed |
| US-20100324011-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-23 | — | — | US | disclosed |
| US-7312229-B2 | 21-Heterocyclic-4-azasteroid derivatives as androgen receptor modulators | MERCK & CO., INC. (US) | 2007-12-25 | — | — | US | disclosed |
| US-20070088047-A1 | 21-Heterocyclic-4-azasteroid derivatives as androgen receptor modulators | MERCK SHARP & DOHME CORP. | 2007-04-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100324011-A1 | AZETIDINYL DIAMIDES AS MONOACYLGLYCEROL LIPASE INHIBITORS | PNLIP, LPL, LIPA | TNKS2 3093/4885DDAH1 150/4885KDM5B 1602/4885 |
| US-20070088047-A1 | 21-Heterocyclic-4-azasteroid derivatives as androgen receptor modulators | NR5A1, AR, NR3C1 | TNKS2 1699/4885DDAH1 3529/4885KDM5B 1384/4885 |
| US-10729738-B2 | Hindered disulfide drug conjugates | STS, TST, SCLY | TNKS2 4577/4885DDAH1 659/4885KDM5B 2432/4885 |
| US-20170112891-A1 | HINDERED DISULFIDE DRUG CONJUGATES | STS, TST, SCLY | TNKS2 4577/4885DDAH1 659/4885KDM5B 2432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.