Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 11/20 | 0.50 |
| ▸ | DRD4 | P21917 | 11/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | CCR5 | P51681 | 2/20 | 0.47 |
| ▸ | KDM1A | O60341 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161120 | 0.79 | DRD2 (0.74) | DRD2DRD4 | |
| SCHEMBL6160574 | 0.74 | SLC6A2 (0.53) | DRD2DRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL13898517 | 0.74 | CCR5 (0.60) | DRD2DRD4CCR5 | |
| SCHEMBL3892595 | 0.74 | CCR5 (0.60) | DRD2DRD4CCR5 | |
| SCHEMBL6161706 | 0.72 | DRD2 (0.78) | DRD2DRD4 | |
| SCHEMBL7723133 | 0.72 | HTR1A (0.50) | DRD2SLC6A2SLC6A4SLC6A3HTR1A | |
| SCHEMBL445421 | 0.71 | DRD2 (0.69) | DRD2DRD4 | |
| SCHEMBL8211043 | 0.71 | SLC6A2 (0.57) | DRD2DRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL5363060 | 0.71 | DRD2 (0.60) | DRD2DRD4SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL6160819 | 0.71 | DRD2 (0.55) | DRD2DRD4SLC6A2SLC6A4SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |