Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.50 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 7/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.43 |
| ▸ | KDM1A | O60341 | 2/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6161129 | 0.77 | HTR1A (0.52) | HTR1ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL8211064 | 0.74 | CACNA1G (0.39) | MEN1KMT2A | |
| SCHEMBL13898484 | 0.72 | SIGMAR1 (0.47) | HTR1AMEN1KMT2ADRD2 | |
| SCHEMBL7723129 | 0.72 | DRD2 (0.50) | HTR1ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL6159547 | 0.71 | PARK7 (0.36) | HTR1ASLC6A4MEN1KMT2AOPRM1 | |
| SCHEMBL13898515 | 0.70 | OPRL1 (0.51) | MEN1KMT2ADRD2OPRM1 | |
| SCHEMBL7598684 | 0.70 | HTR1A (0.70) | HTR1ASLC6A2SLC6A4SLC6A3MEN1 | |
| SCHEMBL6159481 | 0.70 | OPRL1 (0.44) | OPRM1 | |
| SCHEMBL6161715 | 0.69 | SLC6A2 (0.46) | HTR1ASLC6A2SLC6A4SLC6A3DRD2 | |
| SCHEMBL6159478 | 0.69 | SLC18A3 (0.47) | DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6469010-B1 | COMPOSITION ALSO FOR ALLEVIATION OR TREATMENT OF SYMPTOMS DERIVED FROM SEIZURES, EPILEPSY AND MIGRAINE HEADACHES, AND SUPPRESSION OF CALCIUM ION OVERLOAD | SUNTORY LIMITED (JP) | 2002-10-22 | — | — | US | disclosed |
| US-6048876-A | ANTICONVULSANTS; ANTIEPILEPIC AGENT | SUNTORY LIMITED (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0755923-A1 | AMELIORANT OR REMEDY FOR SYMPTOMS CAUSED BY ISCHEMIC DISEASES AND COMPOUNDS USEFUL THEREFOR | SUNTORY LIMITED (JP) | 1997-01-29 | — | — | EP | disclosed |