SCHEMBL7723920

SCHEMBL7723920

C=Cc1ccc(CC(C(=O)O)(C(=O)O)C(Cc2ccccc2)C(C)(C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
TRPA1 O75762 2/20 0.39
SMN1; SMN2 Q16637 1/20 0.36
HIF1A Q16665 1/20 0.36
SRR Q9GZT4 2/20 0.35
THRA P10827 1/20 0.35
THRB P10828 1/20 0.35
OPRM1 P35372 2/20 0.34
OPRD1 P41143 2/20 0.34
OPRK1 P41145 2/20 0.34
MCL1 Q07820 1/20 0.34
CYP1A2 P05177 1/20 0.34
MMP8 P22894 1/20 0.34
PSMD14 O00487 1/20 0.34
LMNA P02545 1/20 0.34
PPARG P37231 2/20 0.33
PPARA Q07869 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5142183 0.70 THRA (0.46) ALDH1A1CYP3A4CYP2C9CYP2C19SMN1; SMN2
SCHEMBL7724200 0.70 ALDH1A1 (0.42) ALDH1A1CYP3A4CYP2C9CYP2C19SMN1; SMN2
SCHEMBL7724203 0.70 ALDH1A1 (0.42) ALDH1A1CYP3A4CYP2C9CYP2C19TRPA1
SCHEMBL5142208 0.69 MMP8 (0.41) ALDH1A1CYP3A4CYP2C9CYP2C19SMN1; SMN2
SCHEMBL3091182 0.68 TAAR1 (0.50) TRPA1CYP1A2
SCHEMBL5144303 0.68 THRA (0.44) ALDH1A1CYP3A4CYP2C9CYP2C19SMN1; SMN2
SCHEMBL5146874 0.67 LDHA (0.52) ALDH1A1CYP2C9SRRCYP1A2PSMD14
Styrene SCHEMBL27607992 0.67 ALDH1A1 (0.61) ALDH1A1CYP3A4CYP2C9CYP2C19SMN1; SMN2
SCHEMBL9332631 0.67 THRA (0.41) ALDH1A1CYP3A4CYP2C9CYP2C19THRA
Isobutylbenzene SCHEMBL27731997 0.66 TSHR (0.45) ALDH1A1CYP2C9TRPA1LMNAPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6399273-B1 Water-processable photoresist compositions BOARD OF REGENTS, UNIVERSITY OF TEXAS SYSTEM 2002-06-04 US disclosed