Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGLL | Q99685 | 2/20 | 0.49 |
| ▸ | EGLN2 | Q96KS0 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 2/20 | 0.35 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7720015 | 0.86 | HPGD (0.43) | TSHRLMNAPAX8NAAA | |
| SCHEMBL7724615 | 0.78 | HTT (0.40) | TSHREPHX2KDM4EHTT | |
| SCHEMBL730392 | 0.78 | PRSS1 (0.38) | TSHRKDM4EHTT | |
| SCHEMBL7725838 | 0.76 | GAA (0.44) | TSHRLMNAPAX8KDM4ENAAA | |
| SCHEMBL7724590 | 0.75 | NAAA (0.40) | TSHRLMNAPAX8KDM4ENAAA | |
| SCHEMBL7720013 | 0.74 | LMNA (0.39) | TSHRLMNAPAX8KDM4ENAAA | |
| SCHEMBL7724611 | 0.74 | MMP13 (0.40) | TSHR | |
| SCHEMBL7720001 | 0.71 | LMNA (0.48) | TSHRLMNAPAX8KDM4ENAAA | |
| SCHEMBL7719994 | 0.70 | ACHE (0.38) | TSHR | |
| SCHEMBL7720010 | 0.69 | PKM (0.42) | TSHRLMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6403818-B1 | ONE POT PROCESS STARTING FROM CARBONYL COMPOUND, ALCOHOL, THIOL OR AMINE, AND PROTECTED HYDROXYDICYANO COMPOUND | EISAI CO., LTD. (JP) | 2002-06-11 | — | — | US | disclosed |