Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 7/20 | 0.39 |
| ▸ | BCHE | P06276 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.32 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.32 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.32 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.32 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4451118 | 0.99 | ACHE (0.39) | ACHEBCHEALDH1A1USP2LMNA | |
| SCHEMBL7118273 | 0.92 | ACHE (0.43) | ACHEBCHEALDH1A1CA12CA1 | |
| SCHEMBL7455420 | 0.77 | ACHE (0.37) | ACHEBCHEALDH1A1SLC6A3 | |
| SCHEMBL9391964 | 0.76 | ACHE (0.38) | ACHEBCHEALDH1A1LMNACA12 | |
| SCHEMBL8133774 | 0.74 | PRCP (0.34) | KMT2AKDM4E | |
| SCHEMBL6788081 | 0.69 | DRD2 (0.31) | GAA | |
| SCHEMBL7229672 | 0.69 | SIGMAR1 (0.38) | ALDH1A1SLC6A4MEN1KMT2A | |
| SCHEMBL7021746 | 0.67 | MAOB (0.33) | ACHESLC6A4SLC6A3MEN1POLB | |
| SCHEMBL22568912 | 0.64 | ACHE (0.47) | ACHEBCHE | |
| SCHEMBL8729417 | 0.63 | ACHE (0.45) | ACHEBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6337409-B1 | 3,3-DISUBSTITUTED NAPHTHOPYRAN; COLOR RESPONSE UPON ULTRAVIOLET LIGHT EXPOSURE EXTENDS TO ORANGE, REDDISH-ORANGE OR PURPLE; BATHYCHROMIC SHIFT OF MAXIMUM ACTIVATED WAVELENGTH; PLASTIC OPHTHALMIC LENSES | VISION-EASE LENS, INC. | 2002-01-08 | — | — | US | disclosed |