Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 8/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 8/20 | 0.36 |
| ▸ | CYP1B1 | Q16678 | 8/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | CYP4B1 | P13584 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | CYP3A5 | P20815 | 1/20 | 0.34 |
| ▸ | CYP2A7 | P20853 | 1/20 | 0.34 |
| ▸ | CYP3A7 | P24462 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9113335 | 0.84 | MAPT (0.36) | CYP1A1CYP1A2CYP1B1MAPTALDH1A1 | |
| SCHEMBL7455420 | 0.84 | ACHE (0.37) | ACHEBCHEALDH1A1NFE2L2 | |
| SCHEMBL7118273 | 0.78 | ACHE (0.43) | ACHEBCHEMAPTALDH1A1CA12 | |
| SCHEMBL7728093 | 0.76 | ACHE (0.39) | ACHEBCHEMAPTALDH1A1CA12 | |
| SCHEMBL4451118 | 0.75 | ACHE (0.39) | ACHEBCHEALDH1A1LMNA | |
| SCHEMBL7021746 | 0.73 | MAOB (0.33) | ACHECA12CA1CA2CA7 | |
| SCHEMBL6918195 | 0.69 | HTT (0.33) | CYP1A2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL7229672 | 0.67 | SIGMAR1 (0.38) | ALDH1A1 | |
| SCHEMBL9114805 | 0.64 | KDM4E (0.40) | MAPTALDH1A1NPC1RAB9ACA12 | |
| SCHEMBL6793677 | 0.63 | KIF11 (0.37) | MAPTNPC1RAB9ALMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1994020869-A1 | NOVEL BENZOPYRANS | PPG INDUSTRIES, INC. (US) | 1994-09-15 | — | — | WO | claimed |
| WO-1994020869-A1 | NOVEL BENZOPYRANS | PPG INDUSTRIES, INC. (US) | 1994-09-15 | — | — | WO | disclosed |