Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 9/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 9/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | GHSR | Q92847 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731754 | 0.90 | OPRM1 (0.34) | OPRM1OPRD1OPRK1EPHX1 | |
| SCHEMBL7733093 | 0.89 | SIGMAR1 (0.34) | OPRM1OPRD1OPRK1EPHX1 | |
| SCHEMBL10652906 | 0.77 | CYP1A2 (0.40) | NFE2L2ALDH1A1L3MBTL1 | |
| SCHEMBL7734349 | 0.76 | SLC6A4 (0.43) | OPRM1OPRK1 | |
| SCHEMBL9177824 | 0.72 | SLC6A3 (0.42) | OPRM1 | |
| SCHEMBL8435345 | 0.72 | OPRM1 (0.41) | OPRM1OPRK1 | |
| SCHEMBL9177828 | 0.72 | SLC6A3 (0.42) | OPRM1 | |
| SCHEMBL6363195 | 0.70 | ALDH1A1 (0.43) | NFE2L2ALDH1A1L3MBTL1 | |
| SCHEMBL6363196 | 0.70 | ALDH1A1 (0.43) | NFE2L2ALDH1A1L3MBTL1 | |
| SCHEMBL10612749 | 0.69 | OPRD1 (0.36) | OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6476266-B1 | Diamino compound and production process for the same | CHISSO CORPORATION (JP) | 2002-11-05 | — | — | US | disclosed |