SCHEMBL7734101

SCHEMBL7734101

CC(=O)c1ccc(N(C(C)=O)c2snc(C)c2Cl)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 3/20 0.38
KMT2A Q03164 3/20 0.38
APAF1 O14727 1/20 0.38
TDP2 O95551 1/20 0.38
NSD2 O96028 1/20 0.38
CASP3 P42574 1/20 0.38
CACNA1B Q00975 1/20 0.38
APBA1 Q02410 1/20 0.38
HKDC1 Q2TB90 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
APOBEC3G Q9HC16 1/20 0.38
SAE1 Q9UBE0 1/20 0.38
UBA2 Q9UBT2 1/20 0.38
NPC1 O15118 4/20 0.36
RAB9A P51151 4/20 0.36
MAPT P10636 4/20 0.35
KDM4E B2RXH2 1/20 0.35
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27517859 0.86 KMT2A (0.41) MEN1KMT2AAPAF1TDP2NSD2
SCHEMBL1927467 0.67 NPSR1 (0.62) MEN1KMT2AAPAF1TDP2NSD2
SCHEMBL7735892 0.64 RAB9A (0.46) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL5174398 0.63 NOS3 (0.50) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL28763259 0.62 MT-CO2 (0.57) MEN1KMT2AAPAF1TDP2NSD2
SCHEMBL8191180 0.61 MAPT (0.55) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL874506 0.60 MAPT (0.50) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL6686244 0.60 MAPT (0.55) MEN1KMT2ANPC1RAB9AMAPT
SCHEMBL50646 0.60 MAPT (0.68) KMT2ANPC1RAB9AMAPTKDM4E
SCHEMBL1129559 0.60 ALDH1A1 (0.52) MEN1KMT2ANPC1RAB9AMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6403622-B1 FOR CONTROLLING INSECTS, ARACHNIDS, NEMATODES BAYER AKTIENGESELLSCHAFT (DE) 2002-06-11 US disclosed
CN-1329611-A Phenylacetic acid heterocyclyl amides having an insecticidal effect BAYER AG (DE) 2002-01-02 CN disclosed
EP-1119569-A1 PHENYLACETIC ACID HETEROCYCLYL AMIDES HAVING AN INSECTICIDAL EFFECT Bayer Aktiengesellschaft (DE) 2001-08-01 EP disclosed
WO-2000020415-A1 PHENYLACETIC ACID HETEROCYCLYL AMIDES HAVING AN INSECTICIDAL EFFECT BAYER AKTIENGESELLSCHAFT (DE) 2000-04-13 WO disclosed