Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.38 |
| ▸ | LNPEP | Q9UIQ6 | 5/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 4/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 2/20 | 0.32 |
| ▸ | ZAP70 | P43403 | 2/20 | 0.32 |
| ▸ | TRPV1 | Q8NER1 | 6/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7732369 | 0.88 | NPC1 (0.34) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| Trifluoroacetic Acid SCHEMBL7723297 | 0.87 | RAB9A (0.41) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL7735983 | 0.85 | RAB9A (0.44) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL7723198 | 0.80 | TRPV1 (0.38) | LTA4HNPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL7730721 | 0.79 | LTA4H (0.40) | LTA4HLNPEPERAP2ERAP1NPC1 | |
| SCHEMBL7733828 | 0.77 | DAGLA (0.38) | LTA4HLNPEPERAP2ERAP1SRC | |
| SCHEMBL7733896 | 0.77 | RAB9A (0.38) | NPC1RAB9AKDM4EALDH1A1HPGD | |
| SCHEMBL7733986 | 0.76 | PSMD14 (0.31) | — | |
| Trifluoroacetic Acid SCHEMBL8360682 | 0.76 | LNPEP (0.35) | LTA4HLNPEPERAP2ERAP1SRC | |
| Trifluoroacetic Acid SCHEMBL7733824 | 0.75 | MMP2 (0.39) | LTA4HLNPEPERAP2ERAP1SRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |