Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.37 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.35 |
| ▸ | F2R | P25116 | 2/20 | 0.35 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.35 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.35 |
| ▸ | CTSC | P53634 | 2/20 | 0.35 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | SRC | P12931 | 1/20 | 0.34 |
| ▸ | ZAP70 | P43403 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.34 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP3 | P08254 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL7732324 | 0.92 | SLC7A11 (0.37) | MMP2F2RCTSCLTA4HSRC | |
| Trifluoroacetic Acid SCHEMBL7731056 | 0.90 | PRSS1 (0.38) | MMP2DAGLALNPEPLTA4H | |
| Trifluoroacetic Acid SCHEMBL7735541 | 0.89 | CCR3 (0.41) | MMP2DAGLALNPEPERAP2ERAP1 | |
| SCHEMBL7733828 | 0.88 | DAGLA (0.38) | MMP2CES1DAGLALNPEPF2R | |
| Trifluoroacetic Acid SCHEMBL7723297 | 0.84 | RAB9A (0.41) | — | |
| Trifluoroacetic Acid SCHEMBL7732364 | 0.83 | PRSS1 (0.40) | MMP2LNPEPERAP2LTA4HSRC | |
| SCHEMBL7861009 | 0.82 | MMP2 (0.40) | MMP2LNPEPERAP2ERAP1CTSC | |
| Trifluoroacetic Acid SCHEMBL8360682 | 0.81 | LNPEP (0.35) | LNPEPF2RERAP2ERAP1LTA4H | |
| SCHEMBL7730721 | 0.80 | LTA4H (0.40) | MMP2LNPEPERAP2ERAP1LTA4H | |
| SCHEMBL7732329 | 0.79 | ZAP70 (0.34) | DAGLACTSCLTA4HSRCZAP70 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| WO-1999037667-A1 | EFFLUX PUMP INHIBITORS | MICROCIDE PHARMACEUTICALS, INC. (US) | 1999-07-29 | — | — | WO | disclosed |