Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | CTSK | P43235 | 3/20 | 0.36 |
| ▸ | CTSS | P25774 | 2/20 | 0.36 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MMP1 | P03956 | 1/20 | 0.34 |
| ▸ | MMP3 | P08254 | 1/20 | 0.34 |
| ▸ | MMP9 | P14780 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | BRD4 | O60885 | 1/20 | 0.32 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7731051 | 0.92 | LMNA (0.39) | MAPTCTSKNPSR1MMP1MMP3 | |
| SCHEMBL7731104 | 0.91 | MAPT (0.39) | MAPTCTSKCTSSNPSR1MMP1 | |
| SCHEMBL7723247 | 0.90 | MAPT (0.38) | MAPTCTSKCTSSNPSR1MMP1 | |
| SCHEMBL7723226 | 0.84 | MAPT (0.38) | MAPTCTSKCTSSNPSR1MMP1 | |
| SCHEMBL7732168 | 0.79 | ADORA3 (0.37) | MAPTCTSKCTSSNPSR1MMP1 | |
| SCHEMBL7731071 | 0.78 | BCHE (0.45) | CTSKCTSSNPSR1MMP1MMP3 | |
| SCHEMBL7730692 | 0.73 | CTSL (0.42) | MAPTCTSKCTSSCTSLCTSB | |
| SCHEMBL7723243 | 0.72 | CTSL (0.43) | CTSKCTSSCTSLCTSBMMP1 | |
| SCHEMBL7732045 | 0.72 | CTSL (0.36) | CTSKCTSSCTSLCTSBPTPN2 | |
| SCHEMBL7723327 | 0.70 | MAPT (0.44) | MAPTCTSKNPSR1MMP1MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |