Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | CTSB | P07858 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | PPARD | Q03181 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.32 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.31 |
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.31 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7733852 | 0.89 | LMNA (0.37) | DAGLA | |
| SCHEMBL7731117 | 0.89 | FAAH (0.35) | PPARGPPARAPTPN2PTPN1DAGLA | |
| SCHEMBL7734187 | 0.89 | F9 (0.30) | — | |
| Trifluoroacetic Acid SCHEMBL7732038 | 0.78 | CTSL (0.41) | CTSLCTSBCTSSCTSKPPARG | |
| SCHEMBL7723243 | 0.77 | CTSL (0.43) | CTSLCTSBCTSSCTSKPTPN2 | |
| SCHEMBL7730692 | 0.76 | CTSL (0.42) | CTSLCTSBCTSSCTSKPTPN2 | |
| SCHEMBL7723163 | 0.75 | HPGD (0.39) | PPARGPPARDPPARA | |
| SCHEMBL7732041 | 0.72 | CTSL (0.39) | CTSLCTSBCTSSCTSKPPARG | |
| SCHEMBL7735575 | 0.72 | MAPT (0.37) | CTSLCTSBCTSSCTSKPTPN2 | |
| SCHEMBL7732434 | 0.68 | CTSL (0.43) | CTSLCTSBCTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6436980-B1 | TRANSPORT PROTEIN SUPPRESSORS; MICROBIOCIDES | ESSENTIAL THERAPEUTICS, INC. | 2002-08-20 | — | — | US | disclosed |
| US-6204279-B1 | SECONDARY AMIDE CONTAINING BENZOXAZOLE DERIVATIVES | MICROCIDE PHARMACEUTICALS, INC. | 2001-03-20 | — | — | US | disclosed |