Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A known ✓ | P27815 | 1/20 | 0.44 |
| ▸ | PDE4B known ✓ | Q07343 | 1/20 | 0.44 |
| ▸ | PDE4D known ✓ | Q08499 | 1/20 | 0.44 |
| ▸ | CA2 known ✓ | P00918 | 1/20 | 0.40 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.40 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.40 |
| ▸ | RAD51 | Q06609 | 8/20 | 0.76 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | USP2 | O75604 | 2/20 | 0.49 |
| ▸ | LTA | P01374 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.49 |
| ▸ | PDE2A | O00408 | 1/20 | 0.44 |
| ▸ | PDE5A | O76074 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6815526 | 1.00 | RAD51 (0.76) | RAD51ALDH1A1CYP3A4MAPTTDP1 | |
| SCHEMBL29405878 | 1.00 | RAD51 (0.76) | RAD51ALDH1A1CYP3A4MAPTTDP1 | |
| Potassium Ion SCHEMBL10633167 | 0.97 | RAD51 (0.72) | RAD51ALDH1A1CYP3A4MAPTTDP1 | |
| Potassium Ion SCHEMBL10633160 | 0.97 | RAD51 (0.72) | RAD51ALDH1A1CYP3A4MAPTTDP1 | |
| SCHEMBL29702569 | 0.92 | RAD51 (0.67) | RAD51ALDH1A1CYP3A4MAPTTDP1 | |
| SCHEMBL29626956 | 0.91 | RAD51 (0.66) | RAD51ALDH1A1CYP3A4MAPTTDP1 | |
| SCHEMBL2391195 | 0.91 | RAD51 (0.66) | RAD51ALDH1A1CYP3A4MAPTTDP1 | |
| SCHEMBL6050517 | 0.91 | RAD51 (0.66) | RAD51ALDH1A1CYP3A4MAPTTDP1 | |
| SCHEMBL27616742 | 0.88 | RAD51 (0.62) | RAD51ALDH1A1CYP3A4MAPTTDP1 | |
| SCHEMBL7555160 | 0.85 | RAD51 (0.59) | RAD51ALDH1A1CYP3A4MAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10788502-B2 | Erythrocyte sedimentation inhibitor | FUJIMORI KOGYO CO., LTD. (JP) | 2020-09-29 | — | — | US | claimed |
| US-20170010289-A1 | ERYTHROCYTE SEDIMENTATION INHIBITOR | FUJIMORI KOGYO CO., LTD. (JP) | 2017-01-12 | — | — | US | claimed |
| EP-3104178-A1 | ERYTHROCYTE SEDIMENTATION INHIBITOR | Fujimori Kogyo Co., Ltd. (JP) | 2016-12-14 | — | — | EP | claimed |
| EP-0019712-B1 | PROCESS FOR PARTIAL REDUCTION OF POLYNITRODIARYL COMPOUNDS | BAYER AG (DE) | 1982-12-15 | — | — | EP | claimed |
| US-4348335-A | Process for the partial reduction of polynitrated diaryl compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | claimed |
| US-3936497-A | HYDROGENATION OF DINITRO WITH NICKEL CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-02-03 | — | — | US | claimed |
| JP-4293969-A | — | — | None | — | — | JP | disclosed |
| US-12408914-B2 | Systems and methods for customizing mechanical strength in stimuli-responsive bioabsorbable materials | CILAG GMBH INTERNATIONAL (CH) | 2025-09-09 | — | — | US | disclosed |
| EP-4242628-B1 | REDUCTION OF ERYTHROCYTE SEDIMENTATION RATE | BIOMATRICA INC (US) | 2025-07-02 | — | — | EP | disclosed |
| EP-4543502-A1 | SYSTEMS AND METHODS FOR CUSTOMIZING MECHANICAL STRENGTH IN STIMULI-RESPONSIVE BIOABSORBABLE MATERIALS | Cilag GmbH International (CH) | 2025-04-30 | — | — | EP | disclosed |
| WO-2024261659-A1 | SYSTEMS AND METHODS FOR CUSTOMIZING MECHANICAL STRENGTH IN STIMULI-RESPONSIVE BIOABSORBABLE MATERIALS | CILAG GMBH INTERNATIONAL (CH) | 2024-12-26 | — | — | WO | disclosed |
| US-20240423620-A1 | COMPRESSIBLE SURGICAL ADJUNCTS, CARTRIDGES, AND CARTRIDGE ASSEMBLIES AND METHODS OF MAKING SURGICAL ADJUNCTS | CILAG GMBH INTERNATIONAL (CH) | 2024-12-26 | — | — | US | disclosed |
| US-20240423617-A1 | SYSTEMS AND METHODS FOR CUSTOMIZING MECHANICAL STRENGTH IN STIMULI-RESPONSIVE BIOABSORBABLE MATERIALS | CILAG GMBH INTERNATIONAL (CH) | 2024-12-26 | — | — | US | disclosed |
| US-5041632-A | Process for the preparation of 4,4'-dinitrostilbene-2,2-disulfonic acid | CIBA-GEIGY CORPORATION (US) | 1991-08-20 | — | — | US | disclosed |
| US-4719051-A | Process for the preparation of 4,4'-dinitrostilbene-2,2'-disulfonic acid and its salts | CIBA-GEIGY CORPORATION (US) | 1988-01-12 | — | — | US | disclosed |
| US-4348335-A | Process for the partial reduction of polynitrated diaryl compounds | BAYER AKTIENGESELLSCHAFT (DE) | 1982-09-07 | — | — | US | disclosed |
| US-4133828-A | Manufacture of dimethylaminobenzenesulfonates | BASF AKTIENGESELLSCHAFT (DE) | 1979-01-09 | — | — | US | disclosed |
| US-3989743-A | Process for the preparation of 4,4'-diaminostilbene-2,2'-disulphonic acid | BAYER AKTIENGESELLSCHAFT (DT) | 1976-11-02 | — | — | US | disclosed |
| US-3936497-A | HYDROGENATION OF DINITRO WITH NICKEL CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-02-03 | — | — | US | disclosed |
| US-3936497-A | HYDROGENATION OF DINITRO WITH NICKEL CATALYST | SUMITOMO CHEMICAL COMPANY, LIMITED (JA) | 1976-02-03 | — | — | US | disclosed |