SCHEMBL7747533

SCHEMBL7747533

O=C=C1CC(CCC(=O)N2CCC[C@@H](C(=O)O)C2)CCN1OCc1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 13/20 0.46
ITGA2B P08514 13/20 0.46
ALDH1A1 P00352 2/20 0.44
F2R P25116 3/20 0.43
HPGD P15428 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
KDM4E B2RXH2 1/20 0.39
MAPK1 P28482 1/20 0.39
NPC1 O15118 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
POLB P06746 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7448545 0.80 SMN1; SMN2 (0.53) ALDH1A1SMN1; SMN2NPC1CYP2C19POLB
SCHEMBL6539363 0.78 SMN1; SMN2 (0.62) ITGB3ITGA2BALDH1A1F2RSMN1; SMN2
SCHEMBL6539357 0.78 SMN1; SMN2 (0.62) ITGB3ITGA2BALDH1A1F2RSMN1; SMN2
SCHEMBL8549480 0.78 BCHE (0.35) SMN1; SMN2MAPK1NPC1CYP2D6CYP2C9
SCHEMBL27339333 0.76 ITGB3 (0.52) ITGB3ITGA2BALDH1A1F2RHPGD
SCHEMBL17646360 0.72 ALDH1A1 (0.72) ALDH1A1HPGDSMN1; SMN2KDM4ENPC1
SCHEMBL7311015 0.72 ALDH1A1 (0.72) ALDH1A1HPGDSMN1; SMN2KDM4ENPC1
SCHEMBL7398369 0.70 GRIN2B (0.35) ALDH1A1CYP2D6CYP2C9
SCHEMBL25453024 0.69 MEN1 (0.57) ITGB3ITGA2BALDH1A1F2R
SCHEMBL3277860 0.69 SMN1; SMN2 (0.71) ALDH1A1HPGDSMN1; SMN2KDM4ENPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010051730-A1 Beta-alanine derivative and a process for the preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 2001-12-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010051730-A1 Beta-alanine derivative and a process for the preparation thereof F13B, FGB, TGFB1 ITGB3 52/4885ITGA2B 14/4885ALDH1A1 416/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.