Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCTPP1 | Q9H773 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11485255 | 0.77 | ALDH1A1 (0.40) | DCTPP1KDM4EMAPTLMNAPPARG | |
| SCHEMBL8927745 | 0.76 | SLC2A1 (0.43) | KDM4EMAPTLMNAPPARGCYP1A2 | |
| SCHEMBL8437208 | 0.74 | AR (0.36) | DCTPP1KDM4EMAPTLMNAPPARG | |
| SCHEMBL8623725 | 0.74 | KDM4E (0.50) | DCTPP1KDM4ELMNAPPARGCYP1A2 | |
| SCHEMBL4966244 | 0.73 | NR1I2 (0.49) | MAPTLMNAPPARGCNR2CYP1A2 | |
| SCHEMBL10971739 | 0.70 | KDM4E (0.48) | DCTPP1KDM4ELMNACYP1A2AGTR1 | |
| SCHEMBL4969422 | 0.68 | F2 (0.50) | KDM4EMAPTLMNAHPGDHSD17B10 | |
| SCHEMBL1259427 | 0.67 | DCTPP1 (0.41) | DCTPP1KDM4ELMNACNR2CNR1 | |
| SCHEMBL25005841 | 0.66 | ACSS2 (0.43) | — | |
| SCHEMBL11768622 | 0.65 | CYP1A2 (0.36) | KDM4EMAPTPPARGCYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0597304-B1 | Use of substituted benzimidazoles for combating parasitic protozoas | BAYER AG (DE) | 2001-01-10 | — | — | EP | disclosed |
| US-5877195-A | INSECTICIDES | BAYER AKTIENGESELLSCHAFT (DE) | 1999-03-02 | — | — | US | disclosed |
| EP-0667863-B1 | 2-PERHALOGENALKYL-SUBSTITUTED BENZIMIDAZOLES, THEIR PREPARATION AND THEIR USE AS PESTICIDES | BAYER AG (DE) | 1998-06-03 | — | — | EP | disclosed |
| US-5482956-A | ANTIPROTOZOA AGENTS FOR ANIMALS OR INSECTS | BAYER AKTIENGESELLSCHAFT (DE) | 1996-01-09 | — | — | US | disclosed |
| EP-0597304-A1 | Use of substituted benzimidazoles | BAYER AG (DE) | 1994-05-18 | — | — | EP | disclosed |