Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.37 |
| ▸ | CTSG | P08311 | 1/20 | 0.37 |
| ▸ | CTRC | Q99895 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GMNN | O75496 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12099135 | 0.83 | LMNA (0.47) | LMNAADORA3F2ELANECTSG | |
| SCHEMBL22063690 | 0.83 | LMNA (0.47) | LMNAADORA3F2ELANECTSG | |
| SCHEMBL1362950 | 0.81 | LMNA (0.46) | LMNAADORA3F2ELANECTSG | |
| SCHEMBL25408450 | 0.79 | LMNA (0.49) | LMNAADORA3F2ELANECTSG | |
| SCHEMBL7687783 | 0.74 | RIPK1 (0.38) | NPSR1KMT2A | |
| SCHEMBL8716129 | 0.73 | ALDH1A1 (0.40) | LMNAADORA3ALDH1A1MGLLMEN1 | |
| SCHEMBL75835 | 0.73 | LMNA (0.40) | LMNAADORA3F2ELANECTSG | |
| SCHEMBL75836 | 0.73 | LMNA (0.40) | LMNAADORA3F2ELANECTSG | |
| SCHEMBL4748698 | 0.71 | LMNA (0.48) | LMNAADORA3F2ELANECTSG | |
| SCHEMBL13687172 | 0.71 | GAA (0.59) | LMNAADORA3ALDH1A1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0983258-A4 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO CO (US) | 2001-01-17 | — | — | EP | claimed |
| EP-0983258-A1 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO COMPANY (US) | 2000-03-08 | — | — | EP | claimed |
| WO-1998039316-A1 | N-HYDROXY 4-SULFONYL BUTANAMIDE COMPOUNDS | MONSANTO COMPANY (US) | 1998-09-11 | — | — | WO | claimed |