Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.44 |
| ▸ | CA2 | P00918 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
| ▸ | CA9 | Q16790 | 1/20 | 0.44 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.44 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4712192 | 0.87 | CA1 (0.50) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL4689119 | 0.84 | MEN1 (0.46) | MAPTCA1CA2MEN1KMT2A | |
| SCHEMBL2208167 | 0.83 | MAPT (0.47) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL498352 | 0.82 | LOXL2 (0.46) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL27487116 | 0.81 | CFTR (0.41) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL2574861 | 0.78 | ESR1 (0.44) | CA1CA2CA12CA7CA9 | |
| SCHEMBL28113312 | 0.77 | TDP1 (0.44) | MAPTTDP1HPGDMEN1KMT2A | |
| SCHEMBL7751798 | 0.75 | MAPT (0.49) | MAPTCA1CA2TDP1CA12 | |
| SCHEMBL28149485 | 0.75 | LMNA (0.33) | MAPTCA1CA2CA9HPGD | |
| SCHEMBL18394314 | 0.74 | ALDH1A1 (0.48) | MAPTTDP1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1293034-C | New gamma selective retinoids | HOFFMANN LA ROCHE (CH) | 2007-01-03 | — | — | CN | disclosed |
| CN-1430596-A | New gamma selective retinoids | HOFFMANN LA ROCHE (CH) | 2003-07-16 | — | — | CN | disclosed |
| US-20010034448-A1 | New compounds, their preparation and use | MURRAY ANTHONY (GB) | 2001-10-25 | — | — | US | disclosed |
| CN-1302292-A | Aminoisoquinoline derivatives | AJINOMOTO KK (JP) | 2001-07-04 | — | — | CN | disclosed |
| EP-1077920-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 2001-02-28 | — | — | EP | disclosed |
| CN-1243505-A | Benzamidine derivatives | AJINOMOTO KK (JP) | 2000-02-02 | — | — | CN | disclosed |
| WO-1999058487-A1 | NEW COMPOUNDS, THEIR PREPARATION AND USE | NOVO NORDISK A/S (DK) | 1999-11-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010034448-A1 | New compounds, their preparation and use | GPR119, SLC5A1, SLC5A2 | MAPT 3618/4885CA1 3435/4885CA2 1626/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.