Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.32 |
| ▸ | ARNT | P27540 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10855157 | 0.73 | OPRK1 (0.48) | CYP1A2OPRK1CYP2D6AKR1B1HPGD | |
| SCHEMBL5152089 | 0.72 | TAAR1 (0.38) | CYP1A2NPC1RAB9ACYP2D6SMN1; SMN2 | |
| SCHEMBL5149885 | 0.71 | SMN1; SMN2 (0.44) | NPC1RAB9ASMN1; SMN2TP53HPGD | |
| SCHEMBL7878527 | 0.69 | GPR35 (0.44) | CYP3A4SMN1; SMN2TP53HPGDVCAM1 | |
| SCHEMBL26912419 | 0.69 | OPRK1 (0.43) | CYP1A2OPRK1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL30684288 | 0.69 | OPRK1 (0.43) | CYP1A2OPRK1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL11303709 | 0.68 | ALDH1A1 (0.48) | NPC1RAB9ASMN1; SMN2LMNATP53 | |
| SCHEMBL7752161 | 0.68 | VCAM1 (0.35) | CYP1A2LMNAMEN1KMT2AMAPT | |
| SCHEMBL7752167 | 0.68 | VCAM1 (0.35) | CYP1A2LMNAMEN1KMT2AMAPT | |
| SCHEMBL31551958 | 0.67 | CES2 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0781757-B1 | Process for the preparation of fluorinated benzoic acids | ABBOTT LAB (US) | 2001-01-03 | — | — | EP | disclosed |
| EP-0781757-A1 | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-07-02 | — | — | EP | disclosed |
| US-5637765-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-06-10 | — | — | US | disclosed |
| US-5633399-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1997-05-27 | — | — | US | disclosed |
| US-5576455-A | Process for the preparation of fluorinated benzoic acids | ABBOTT LABORATORIES (US) | 1996-11-19 | — | — | US | disclosed |
| EP-0610384-A4 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS. | ABBOTT LAB (US) | 1995-01-25 | — | — | EP | disclosed |
| EP-0610384-A1 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS. | ABBOTT LAB (US) | 1994-08-17 | — | — | EP | disclosed |
| WO-1993009077-A2 | PROCESS FOR THE PREPARATION OF FLUORINATED BENZOIC ACIDS | ABBOTT LABORATORIES (US) | 1993-05-13 | — | — | WO | disclosed |