Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 3/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7749227 | 0.84 | ELANE (0.43) | HPGDKMT2ACYP2C19NR1I2PPARG | |
| SCHEMBL6720862 | 0.73 | KMT2A (0.45) | LMNAALDH1A1MAPTRAB9AHPGD | |
| SCHEMBL6725779 | 0.73 | KMT2A (0.64) | LMNAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL6723591 | 0.71 | THRA (0.46) | LMNAALDH1A1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL977546 | 0.69 | FFAR1 (0.59) | LMNAFFAR1ALDH1A1MAPTRAB9A | |
| SCHEMBL6721207 | 0.68 | GABRA1 (0.59) | LMNAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL976893 | 0.67 | FFAR1 (0.63) | FFAR1HPGDKMT2AMEN1 | |
| SCHEMBL18646100 | 0.65 | ALDH1A1 (0.55) | LMNAALDH1A1MAPTRAB9ANPC1 | |
| SCHEMBL6723918 | 0.65 | ALDH1A1 (0.47) | LMNAALDH1A1SRD5A2KMT2ASLC6A2 | |
| SCHEMBL10493728 | 0.65 | ALDH1A1 (0.60) | LMNAALDH1A1MAPTRAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |