Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 6/20 | 0.43 |
| ▸ | NSD2 | O96028 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.36 |
| ▸ | EYA3 | Q99504 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7753141 | 0.84 | LMNA (0.40) | CYP2C19HPGDEYA3NR1I2PPARG | |
| SCHEMBL6721207 | 0.69 | GABRA1 (0.59) | ELANECYP2C19HPGDPTGS1EYA3 | |
| SCHEMBL6728507 | 0.68 | MEN1 (0.49) | ELANENSD2CYP2C19CYP1A2HPGD | |
| SCHEMBL3951337 | 0.66 | KMT2A (0.53) | HPGDHDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL31325690 | 0.66 | KMT2A (0.53) | HPGDHDAC1HDAC8HDAC6MEN1 | |
| SCHEMBL11426657 | 0.66 | HPGD (0.47) | CYP1A2HPGDPTGS1PTGS2MEN1 | |
| SCHEMBL5303103 | 0.66 | TTR (0.52) | CYP2C19PTGS1EYA3GABRA1GABRB1 | |
| SCHEMBL6725083 | 0.65 | ESR1 (0.49) | ELANENSD2HPGDMEN1KMT2A | |
| SCHEMBL6436867 | 0.65 | CYP1A2 (0.68) | CYP2C19CYP1A2CYP2D6HPGDPTGS1 | |
| SCHEMBL6723437 | 0.64 | TUBB4A (0.60) | HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2001036351-A2 | PLASMINOGEN ACTIVATOR INHIBITOR ANTAGONISTS RELATED APPLICATIONS | CORVAS INTERNATIONAL, INC. (US) | 2001-05-25 | — | — | WO | disclosed |