Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 11/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | CYP2A13 | Q16696 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
| ▸ | CHKA | P35790 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9232860 | 0.93 | SIGMAR1 (0.55) | SIGMAR1KDM4ETDP1ALDH1A1POLB | |
| SCHEMBL7756765 | 0.84 | SIGMAR1 (0.58) | SIGMAR1POLBCYP1A2CYP2D6TMEM97 | |
| SCHEMBL7759823 | 0.82 | SIGMAR1 (0.48) | SIGMAR1POLB | |
| Hydrochloric Acid SCHEMBL9514659 | 0.78 | SIGMAR1 (0.64) | SIGMAR1KDM4ETDP1ALDH1A1POLB | |
| SCHEMBL7762764 | 0.78 | KDM4E (0.55) | SIGMAR1KDM4EALDH1A1MAPTTMEM97 | |
| SCHEMBL9230596 | 0.77 | SIGMAR1 (0.54) | SIGMAR1POLBCYP1A2CYP2D6TMEM97 | |
| SCHEMBL9449597 | 0.76 | SIGMAR1 (0.55) | SIGMAR1KDM4ECYP1A2CYP2D6TMEM97 | |
| SCHEMBL7759855 | 0.75 | CCR3 (0.58) | SIGMAR1KDM4EALDH1A1 | |
| Hydrochloric Acid SCHEMBL9449928 | 0.73 | HTR1A (0.51) | SIGMAR1KDM4EPOLBMAPTTMEM97 | |
| SCHEMBL9449807 | 0.73 | DRD2 (0.46) | KDM4EALDH1A1CYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0673934-B1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR (FR) | 2001-04-25 | — | — | EP | claimed |
| CN-1111626-A | Preparation and the pharmaceutical compositions which contain them | ADIR (FR) | 1995-11-15 | — | — | CN | claimed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | claimed |
| EP-0673934-A1 | Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1995-09-27 | — | — | EP | disclosed |