Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | HTR1A | P08908 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 2/20 | 0.46 |
| ▸ | DRD1 | P21728 | 1/20 | 0.46 |
| ▸ | DRD5 | P21918 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | ABCB1 | P08183 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.42 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9449641 | 0.88 | ADRA1D (0.51) | DRD2HTR1ADRD3DRD1DRD5 | |
| SCHEMBL9449660 | 0.83 | HTR1A (0.47) | DRD2HTR1ADRD3HTR2A | |
| SCHEMBL8785466 | 0.81 | DRD2 (0.46) | DRD2HTR1ADRD3DRD1DRD5 | |
| SCHEMBL7759823 | 0.80 | SIGMAR1 (0.48) | DRD2HTR1AKMT2AADRA1AKCNH2 | |
| Hydrochloric Acid SCHEMBL9449928 | 0.80 | HTR1A (0.51) | DRD2HTR1ADRD3DRD1DRD5 | |
| SCHEMBL9449597 | 0.79 | SIGMAR1 (0.55) | HTR1AKDM4EGAACYP1A2CYP2D6 | |
| Hydrochloric Acid SCHEMBL9449688 | 0.78 | ADRA1D (0.61) | DRD2HTR1ADRD1HTR2AADRA1A | |
| Hydrochloric Acid SCHEMBL9437976 | 0.76 | HTR1A (0.60) | DRD2HTR1AHTR2AABCB1ALDH1A1 | |
| SCHEMBL7756765 | 0.76 | SIGMAR1 (0.58) | HTR1ACYP1A2CYP2D6 | |
| SCHEMBL8109164 | 0.75 | SIGMAR1 (0.51) | DRD2MEN1KMT2ACYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5234924-A | Hypotensive agents | ADIR ET COMPAGNIE (FR) | 1993-08-10 | — | — | US | claimed |