Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 3/20 | 0.35 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.33 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.33 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.33 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | GRM3 | Q14832 | 1/20 | 0.31 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.30 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.30 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7761139 | 0.93 | HSD11B1 (0.34) | ALOX5SLC1A3SLC1A2SLC1A1HSD11B1 | |
| SCHEMBL7763689 | 0.85 | ALOX5 (0.33) | ALOX5SLC1A3SLC1A2SLC1A1 | |
| SCHEMBL7760175 | 0.77 | MAPT (0.33) | HSD11B1 | |
| SCHEMBL14931694 | 0.69 | ALOX5 (0.39) | ALOX5SLC1A3SLC1A2SLC1A1GRM2 | |
| SCHEMBL14795120 | 0.69 | ALOX5 (0.42) | ALOX5GRM2GRM3HSD11B1EPHX1 | |
| SCHEMBL14795154 | 0.69 | ALOX5 (0.42) | ALOX5GRM2GRM3HSD11B1EPHX1 | |
| SCHEMBL7761975 | 0.68 | ALOX5 (0.31) | ALOX5 | |
| Trifluoroacetamide SCHEMBL28959533 | 0.68 | CTSD (0.39) | ALOX5EPHX1 | |
| SCHEMBL15525640 | 0.67 | HSD11B1 (0.42) | ALOX5GRM2GRM3HSD11B1EPHX1 | |
| SCHEMBL27564736 | 0.67 | LMNA (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1306503-A | 2-fluoro-2-alkyl alkanoamides with anticonvulsant activity | HEINZ NAU (DE) | 2001-08-01 | — | — | CN | disclosed |
| EP-1089962-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES, INC. (US) | 2001-04-11 | — | — | EP | disclosed |
| WO-1999067199-A1 | 2-FLUORO-2-ALKYL ALKANOAMIDES WITH ANTICONVULSANT ACTIVITY | AMERICAN BIOGENETIC SCIENCES INC. (US) | 1999-12-29 | — | — | WO | disclosed |