SCHEMBL7759836

SCHEMBL7759836

C=CCNCCCc1ccc2c(c1)[S+]([O-])CN2

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.31
CNR2 P34972 1/20 0.31
KCNH2 Q12809 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7761424 0.81 SIGMAR1 (0.46)
SCHEMBL27321209 0.81 SIGMAR1 (0.51) KCNH2
SCHEMBL7756740 0.80 CHRM2 (0.44)
SCHEMBL9685789 0.76 SKP2 (0.41)
SCHEMBL8114298 0.75 HRH1 (0.37)
SCHEMBL9684208 0.75 CA2 (0.36)
SCHEMBL8948251 0.75 CNR1 (0.33) CNR1CNR2
SCHEMBL7756732 0.71 DRD2 (0.45)
SCHEMBL9204489 0.70 KDM4E (0.34)
SCHEMBL7765516 0.70 RECQL (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0673934-B1 Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 2001-04-25 EP disclosed
EP-0673934-A1 Aminoalkyl benzothiazolinones, process for their preparation and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1995-09-27 EP disclosed