Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.34 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.34 |
| ▸ | BACE1 | P56817 | 2/20 | 0.33 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL773437 | 0.86 | MEN1 (0.35) | NR1H4KDM4EALDH1A1MAPTHPGD | |
| SCHEMBL774040 | 0.82 | USP30 (0.38) | USP30CHRM2CHRM1CHRM3BACE1 | |
| SCHEMBL26621923 | 0.72 | LPL (0.41) | KDM4EALDH1A1MAPTHPGDHSD17B10 | |
| SCHEMBL12822400 | 0.72 | MEN1 (0.41) | KDM4EALDH1A1MAPTMEN1KMT2A | |
| SCHEMBL798304 | 0.70 | SMN1; SMN2 (0.44) | CHRM2CHRM1CHRM3KDM4EALDH1A1 | |
| SCHEMBL12817123 | 0.70 | MCL1 (0.36) | CTSSCTSKMCL1NR1D1CHRM2 | |
| SCHEMBL12822172 | 0.69 | GPR55 (0.42) | — | |
| SCHEMBL775018 | 0.69 | LPL (0.40) | KDM4EALDH1A1MAPTHSD17B10KMT2A | |
| SCHEMBL18662581 | 0.69 | LPL (0.40) | KDM4EALDH1A1MAPTHSD17B10KMT2A | |
| SCHEMBL775430 | 0.69 | KDM4E (0.36) | KDM4EALDH1A1HPGDMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8710163-B2 | Pyridyldiamido transition metal complexes, production and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2014-04-29 | — | — | US | disclosed |
| EP-2688895-A1 | PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF | Exxonmobil Chemical Patents Inc. (US) | 2014-01-29 | — | — | EP | disclosed |
| EP-2688897-A1 | PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF | Exxon-Mobil Chemical Patents Inc. (US) | 2014-01-29 | — | — | EP | disclosed |
| US-8394902-B2 | Pyridyldiamido transition metal complexes, production and use thereof | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2013-03-12 | — | — | US | disclosed |
| WO-2012134615-A1 | PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| WO-2012134614-A1 | PYRIDYLDIAMIDO TRANSITION METAL COMPLEXES, PRODUCTION AND USE THEREOF | EXXONMOBIL CHEMICAL PATENTS INC. (US) | 2012-10-04 | — | — | WO | disclosed |
| US-20120071616-A1 | Pyridyldiamido Transition Metal Complexes, Production And Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2012-03-22 | — | — | US | disclosed |
| US-20110301310-A1 | Pyridyldiamido Transition Metal Complexes, Production And Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-12-08 | — | — | US | disclosed |
| US-20110224391-A1 | Pyridyldiamido Transition Metal Complexes, Production and Use Thereof | EXXONMOBIL CHEMICAL PATENTS INC. | 2011-09-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110301310-A1 | Pyridyldiamido Transition Metal Complexes, Production And Use Thereof | PNPO, PLPBP, PDXK | CTSS 4023/4885CTSK 3078/4885MCL1 849/4885 |
| US-20110224391-A1 | Pyridyldiamido Transition Metal Complexes, Production and Use Thereof | PICALM, PARN, PCBP1 | CTSS 3994/4885CTSK 3351/4885MCL1 1003/4885 |
| US-20120071616-A1 | Pyridyldiamido Transition Metal Complexes, Production And Use Thereof | PNPO, PLPBP, PDXK | CTSS 4023/4885CTSK 3078/4885MCL1 849/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.