Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 2/20 | 0.65 |
| ▸ | CASP1 | P29466 | 11/20 | 0.61 |
| ▸ | CTSK | P43235 | 2/20 | 0.56 |
| ▸ | CASP3 | P42574 | 4/20 | 0.55 |
| ▸ | CASP7 | P55210 | 4/20 | 0.55 |
| ▸ | CASP4 | P49662 | 2/20 | 0.55 |
| ▸ | MMP14 | P50281 | 1/20 | 0.55 |
| ▸ | CASP9 | P55211 | 2/20 | 0.55 |
| ▸ | CASP10 | Q92851 | 2/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.55 |
| ▸ | CTSS | P25774 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7764419 | 1.00 | MMP9 (0.65) | MMP9CASP1CTSKCASP3CASP7 | |
| SCHEMBL8401067 | 0.90 | MMP9 (0.59) | MMP9CASP1CTSKCASP3CASP7 | |
| SCHEMBL19015747 | 0.90 | MMP9 (0.62) | MMP9CASP1CTSKMMP14CYP3A4 | |
| SCHEMBL10797754 | 0.89 | CTSL (0.66) | MMP9CTSKMMP14CTSS | |
| SCHEMBL10453892 | 0.86 | CAPN1 (0.61) | CASP1CTSK | |
| SCHEMBL16770335 | 0.85 | CASP3 (0.59) | CASP1CTSKCASP3CASP7CASP4 | |
| SCHEMBL7760223 | 0.85 | CASP1 (0.58) | CASP1CTSKCASP3CASP7CASP4 | |
| SCHEMBL21469067 | 0.85 | ATM (0.68) | MMP9CTSKCYP3A4TSHRCTSS | |
| SCHEMBL30460502 | 0.85 | ATM (0.68) | MMP9CTSKCYP3A4TSHRCTSS | |
| SCHEMBL8530402 | 0.85 | ATM (0.68) | MMP9CTSKCYP3A4TSHRCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0845455-B1 | Addition salts of N-acyl aspartic acid and alpha-arylalkylamines and process for the optical resolution of alpha-arylalkylamines | AJINOMOTO KK (JP) | 2001-05-16 | — | — | EP | disclosed |
| EP-0688760-B1 | Addition salts of acyl-amino acids and alpha-aryl-amines and process for the optical resolution of alpha-arylamines | AJINOMOTO KK (JP) | 1999-06-09 | — | — | EP | disclosed |
| EP-0845455-A1 | Addition salts of acyl-amino acids and alpha-arylamines and process for the optical resolution of alpha-arylamines | Ajinomoto Co., Inc. (JP) | 1998-06-03 | — | — | EP | disclosed |
| EP-0688760-A1 | Addition salts of acyl-amino acids and alpha-aryl-amines and process for the optical resolution of alpha-arylamines | Ajinomoto Co., Inc. (JP) | 1995-12-27 | — | — | EP | disclosed |