Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | NAAA | Q02083 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
| ▸ | DRD1 | P21728 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467098 | 0.83 | HRH1 (0.44) | L3MBTL1TDP1NAAA | |
| SCHEMBL28055680 | 0.82 | MAOA (0.57) | IDO1MAOASIGMAR1 | |
| SCHEMBL8133980 | 0.81 | SIGMAR1 (0.49) | SIGMAR1 | |
| SCHEMBL706330 | 0.80 | IDO1 (0.46) | IDO1L3MBTL1TDP1MAOASIGMAR1 | |
| SCHEMBL104848 | 0.79 | IDO1 (0.48) | IDO1L3MBTL1TDP1MAOASIGMAR1 | |
| SCHEMBL706398 | 0.77 | SIGMAR1 (0.44) | IDO1L3MBTL1TDP1MAOASIGMAR1 | |
| SCHEMBL14030598 | 0.77 | RAB9A (0.57) | IDO1L3MBTL1TDP1MAOASIGMAR1 | |
| Ethylbenzene SCHEMBL6889785 | 0.77 | TP53 (0.64) | — | |
| SCHEMBL703456 | 0.76 | L3MBTL1 (0.44) | IDO1L3MBTL1MAOASIGMAR1CHRM2 | |
| SCHEMBL11733300 | 0.76 | ALDH1A1 (0.45) | DRD3KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268421-B1 | MIXTURES OF POLYTHIOETHERS WITH SILICATE GROUPS FOR REINFORCEMENT WITH CARBON BLACK | HUELS AG (DE) | 2001-07-31 | — | — | US | disclosed |
| EP-0731824-B1 | REINFORCING ADDITIVES | DEGUSSA (DE) | 2001-05-09 | — | — | EP | disclosed |
| EP-0731824-A1 | REINFORCING ADDITIVES | Hüls Silicone Gesellschaft mit beschränkter Haftung (DE) | 1996-09-18 | — | — | EP | disclosed |
| WO-1996010604-A1 | REINFORCING ADDITIVES | HÜLS SILICONE GMBH (DE) | 1996-04-11 | — | — | WO | disclosed |