Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.52 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.52 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.52 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | IDO1 | P14902 | 1/20 | 0.51 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7776308 | 0.93 | MAPT (0.61) | MAPTLMNATSHRNPSR1CYP1A2 | |
| SCHEMBL8655317 | 0.92 | ALDH1A1 (0.56) | MAPTLMNANPSR1CYP1A2CYP3A4 | |
| SCHEMBL8658192 | 0.91 | ALDH1A1 (0.56) | MAPTLMNACYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8667069 | 0.91 | LMNA (0.60) | MAPTLMNATSHRNPSR1MEN1 | |
| SCHEMBL7774529 | 0.90 | LMNA (0.63) | MAPTLMNANPSR1CYP2C19MEN1 | |
| SCHEMBL8658570 | 0.90 | PTGS2 (0.61) | MAPTLMNANPSR1CYP1A2CYP3A4 | |
| SCHEMBL8912421 | 0.88 | GPR27 (0.56) | MAPTLMNATSHRNPSR1CYP1A2 | |
| SCHEMBL7777675 | 0.87 | LMNA (0.60) | MAPTLMNANPSR1MEN1KMT2A | |
| SCHEMBL8659782 | 0.85 | GAA (0.56) | MAPTLMNANPSR1CYP1A2CYP3A4 | |
| SCHEMBL8658342 | 0.83 | LMNA (0.60) | MAPTLMNATSHRMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0788889-B1 | A thermal sensitive recording sheet | JUJO PAPER CO LTD (JP) | 2001-08-08 | — | — | EP | disclosed |
| EP-0699662-B1 | Novel urea (thiourea) derivative and thermal recording sheet using same | JUJO PAPER CO LTD (JP) | 1998-10-21 | — | — | EP | disclosed |
| EP-0788889-A2 | A thermal sensitive recording sheet | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1997-08-13 | — | — | EP | disclosed |
| EP-0699662-A1 | Novel urea (thiourea) derivative and thermal recording sheet using same | NIPPON PAPER INDUSTRIES CO., LTD. (JP) | 1996-03-06 | — | — | EP | disclosed |