SCHEMBL7776308

SCHEMBL7776308

Cc1cccc(NC(=S)Nc2ccc(S(=O)(=O)NC(=O)c3ccccc3)cc2)c1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.61
LMNA P02545 3/20 0.61
ALDH1A1 P00352 6/20 0.57
ALOX12 P18054 4/20 0.54
HPGD P15428 3/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
CA1 P00915 2/20 0.54
CA2 P00918 2/20 0.54
THRB P10828 1/20 0.53
MEN1 O00255 2/20 0.52
KMT2A Q03164 2/20 0.52
CYP1A2 P05177 1/20 0.52
CYP3A4 P08684 1/20 0.52
CYP2D6 P10635 1/20 0.52
CYP2C19 P33261 1/20 0.52
NPSR1 Q6W5P4 1/20 0.52
KCNK3 O14649 1/20 0.52
POLB P06746 1/20 0.52
KCNK9 Q9NPC2 1/20 0.52
IDO1 P14902 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8655317 0.94 ALDH1A1 (0.56) MAPTLMNAALDH1A1ALOX12HPGD
SCHEMBL7770066 0.93 MAPT (0.55) MAPTLMNAALDH1A1ALOX12HPGD
SCHEMBL8658342 0.91 LMNA (0.60) MAPTLMNAALDH1A1MEN1KMT2A
SCHEMBL7777675 0.89 LMNA (0.60) MAPTLMNAALDH1A1ALOX12HPGD
SCHEMBL6295729 0.89 MEN1 (0.61) MAPTLMNAALDH1A1SMN1; SMN2CA1
SCHEMBL8658192 0.88 ALDH1A1 (0.56) MAPTLMNAALDH1A1ALOX12HPGD
SCHEMBL8912421 0.88 GPR27 (0.56) MAPTLMNAALDH1A1ALOX12SMN1; SMN2
SCHEMBL7774529 0.88 LMNA (0.63) MAPTLMNAALDH1A1ALOX12HPGD
SCHEMBL7770076 0.84 RAB9A (0.56) MAPTLMNASMN1; SMN2MEN1KMT2A
SCHEMBL8667069 0.83 LMNA (0.60) MAPTLMNAALDH1A1ALOX12SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788889-B1 A thermal sensitive recording sheet JUJO PAPER CO LTD (JP) 2001-08-08 EP disclosed
EP-0699662-B1 Novel urea (thiourea) derivative and thermal recording sheet using same JUJO PAPER CO LTD (JP) 1998-10-21 EP disclosed
US-5661100-A HAVING HIGH SENSITIVITY, SUPERIOR THERMAL RESISTANCE, WATER RESISTANCE, OIL RESISTANCE NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-26 US disclosed
EP-0788889-A2 A thermal sensitive recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-13 EP disclosed
EP-0699662-A1 Novel urea (thiourea) derivative and thermal recording sheet using same NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-03-06 EP disclosed