Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.38 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.33 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 3/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1498017 | 0.90 | RECQL (0.46) | RECQLCA2TSHRCA1HCAR2 | |
| SCHEMBL29272017 | 0.90 | RECQL (0.46) | RECQLCA2TSHRCA1HCAR2 | |
| SCHEMBL6138906 | 0.88 | RECQL (0.44) | RECQLTSHRNPSR1CA1 | |
| SCHEMBL208567 | 0.87 | RECQL (0.43) | RECQLTSHR | |
| Octane SCHEMBL7762184 | 0.87 | RECQL (0.43) | RECQLTSHR | |
| SCHEMBL4941649 | 0.87 | RECQL (0.43) | RECQLTSHR | |
| SCHEMBL138400 | 0.87 | RECQL (0.43) | RECQLTSHR | |
| SCHEMBL401362 | 0.87 | RECQL (0.43) | RECQLTSHR | |
| SCHEMBL6139132 | 0.87 | RECQL (0.43) | RECQLTSHR | |
| SCHEMBL8376551 | 0.87 | RECQL (0.43) | RECQLTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851005-B1 | Agglomerated pigment, process for producing the same, aqueous pigment dispersion, and water-based ink composition | SEIKO EPSON CORP (JP) | 2001-08-22 | — | — | EP | disclosed |
| US-6083315-A | SULFONATED ORGANIC PIGMENT; BIVALENT OR HIGHER INORGANIC COUNTER IONS EACH HAVING AN AT LEAST UNIVALENT POSITIVE CHARGE; COUNTER-ION-REPLACEMENT AGGLOMERATION | SEIKO EPSON CORPORATION (JP) | 2000-07-04 | — | — | US | disclosed |
| EP-0851005-A2 | Agglomerated pigment, process for producing the same, aqueous pigment dispersion, and water-based ink composition | SEIKO EPSON CORPORATION (JP) | 1998-07-01 | — | — | EP | disclosed |