SCHEMBL30775608

SCHEMBL30775608

CCOP(c1ccccc1)c1ccc(F)cc1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
L3MBTL1 Q9Y468 3/20 0.40
CYP1A2 P05177 1/20 0.40
CYP2D6 P10635 1/20 0.40
CYP2C19 P33261 1/20 0.40
TDP1 Q9NUW8 1/20 0.40
ALDH1A1 P00352 2/20 0.36
KCNH3 Q9ULD8 1/20 0.36
KDM4E B2RXH2 3/20 0.35
MAPK1 P28482 2/20 0.34
TP53 P04637 1/20 0.34
KMT2A Q03164 2/20 0.33
NFE2L2 Q16236 1/20 0.33
TSHR P16473 1/20 0.33
HSD17B10 Q99714 1/20 0.33
NR3C1 P04150 1/20 0.32
SCN9A Q15858 1/20 0.32
ESR1 P03372 1/20 0.31
ESR2 Q92731 1/20 0.31
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7778608 0.92 TDP1 (0.36) L3MBTL1CYP1A2CYP2D6CYP2C19TDP1
SCHEMBL196443 0.88 CYP3A4 (0.39) L3MBTL1TDP1ALDH1A1TP53TSHR
SCHEMBL30775610 0.84 ACHE (0.35) TDP1KDM4ENFE2L2ELANELMNA
SCHEMBL30775606 0.80 SMN1; SMN2 (0.38) L3MBTL1CYP1A2TDP1ALDH1A1KDM4E
SCHEMBL11728040 0.80 KCNN4 (0.33) TDP1TP53
SCHEMBL8336303 0.78 ALDH1A1 (0.40) L3MBTL1CYP1A2CYP2C19TDP1ALDH1A1
SCHEMBL30356626 0.77 ACHE (0.39) NFE2L2LMNA
SCHEMBL7776013 0.77 ACHE (0.39) NFE2L2LMNA
SCHEMBL8638207 0.74 NFE2L2 (0.44) L3MBTL1CYP1A2CYP2D6CYP2C19ALDH1A1
SCHEMBL10709571 0.73 ACHE (0.38) CYP1A2CYP2C19TDP1ALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117362338-A Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound 湖南理工学院 2024-01-09 CN claimed
CN-117362338-A Method for preparing 3, 3-diaryl allyl substituted organic phosphonate compound 湖南理工学院 2024-01-09 CN disclosed