SCHEMBL7776124

SCHEMBL7776124

Cc1ccc(NC(=O)Nc2ccc(S(=O)(=O)NC(=O)c3ccc4ccccc4c3)cc2)cc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 2/20 0.64
GPR27 Q9NS67 1/20 0.60
LMNA P02545 2/20 0.59
RAB9A P51151 3/20 0.55
NPC1 O15118 2/20 0.55
KAT6A Q92794 1/20 0.55
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
ALDH1A1 P00352 1/20 0.54
ALOX12 P18054 1/20 0.54
CA2 P00918 2/20 0.53
TP53 P04637 1/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA4 P22748 1/20 0.53
CA6 P23280 1/20 0.53
CA5A P35218 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA13 Q8N1Q1 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8768061 0.94 RAB9A (0.64) ENPP2GPR27LMNARAB9ANPC1
SCHEMBL8658196 0.91 GPR27 (0.71) ENPP2GPR27LMNARAB9ANPC1
SCHEMBL9176194 0.91 KAT6A (0.64) ENPP2GPR27RAB9ANPC1KAT6A
SCHEMBL8664097 0.91 GPR27 (0.58) ENPP2GPR27LMNARAB9ANPC1
SCHEMBL7776320 0.91 ENPP2 (0.61) ENPP2GPR27LMNARAB9ANPC1
SCHEMBL7647250 0.86 LMNA (0.74) GPR27LMNARAB9ANPC1MEN1
SCHEMBL7774521 0.86 LMNA (0.74) GPR27LMNARAB9ANPC1MEN1
SCHEMBL8767632 0.86 LMNA (0.51) ENPP2GPR27LMNARAB9ANPC1
SCHEMBL7776284 0.86 MEN1 (0.66) LMNARAB9ANPC1MEN1KMT2A
SCHEMBL7774524 0.85 LMNA (0.72) LMNARAB9ANPC1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788889-B1 A thermal sensitive recording sheet JUJO PAPER CO LTD (JP) 2001-08-08 EP disclosed
EP-0699662-B1 Novel urea (thiourea) derivative and thermal recording sheet using same JUJO PAPER CO LTD (JP) 1998-10-21 EP disclosed
US-5661100-A HAVING HIGH SENSITIVITY, SUPERIOR THERMAL RESISTANCE, WATER RESISTANCE, OIL RESISTANCE NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-26 US disclosed
EP-0788889-A2 A thermal sensitive recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-13 EP disclosed
EP-0699662-A1 Novel urea (thiourea) derivative and thermal recording sheet using same NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1996-03-06 EP disclosed