SCHEMBL7776320

SCHEMBL7776320

Cc1ccc(NC(=S)Nc2ccc(S(=O)(=O)NC(=O)c3ccc4ccccc4c3)cc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ENPP2 Q13822 2/20 0.61
GPR27 Q9NS67 1/20 0.58
NPC1 O15118 3/20 0.54
RAB9A P51151 3/20 0.54
TDP1 Q9NUW8 1/20 0.54
KAT6A Q92794 1/20 0.53
ALDH1A1 P00352 4/20 0.52
KDM4E B2RXH2 1/20 0.52
LMNA P02545 2/20 0.51
MAPT P10636 2/20 0.51
ALOX12 P18054 1/20 0.51
HPGD P15428 1/20 0.50
GPR55 Q9Y2T6 1/20 0.49
PPARG P37231 1/20 0.49
F10 P00742 1/20 0.49
PTGS2 P35354 1/20 0.49
NPSR1 Q6W5P4 1/20 0.48
ENPP3 O14638 1/20 0.48
ENPP1 P22413 1/20 0.48
CASP3 P42574 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7777619 0.92 GPR27 (0.68) ENPP2GPR27NPC1RAB9ATDP1
SCHEMBL8912421 0.91 GPR27 (0.56) ENPP2GPR27NPC1RAB9ATDP1
SCHEMBL7776124 0.91 ENPP2 (0.64) ENPP2GPR27NPC1RAB9AKAT6A
SCHEMBL9176194 0.89 KAT6A (0.64) ENPP2GPR27NPC1RAB9AKAT6A
SCHEMBL7774529 0.87 LMNA (0.63) TDP1ALDH1A1KDM4ELMNAMAPT
SCHEMBL8658570 0.87 PTGS2 (0.61) NPC1RAB9ATDP1ALDH1A1KDM4E
SCHEMBL7777675 0.86 LMNA (0.60) NPC1RAB9AALDH1A1LMNAMAPT
SCHEMBL8768061 0.85 RAB9A (0.64) ENPP2GPR27NPC1RAB9AKAT6A
SCHEMBL8658192 0.85 ALDH1A1 (0.56) NPC1RAB9AKAT6AALDH1A1LMNA
SCHEMBL7770066 0.83 MAPT (0.55) NPC1RAB9AALDH1A1KDM4ELMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0788889-B1 A thermal sensitive recording sheet JUJO PAPER CO LTD (JP) 2001-08-08 EP disclosed
US-5661100-A HAVING HIGH SENSITIVITY, SUPERIOR THERMAL RESISTANCE, WATER RESISTANCE, OIL RESISTANCE NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-26 US disclosed
EP-0788889-A2 A thermal sensitive recording sheet NIPPON PAPER INDUSTRIES CO., LTD. (JP) 1997-08-13 EP disclosed