SCHEMBL7776137

SCHEMBL7776137

FC(F)(Cc1ccccc1)c1ccccc1

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.54
CYP2C9 P11712 1/20 0.54
CYP2C19 P33261 1/20 0.54
ALDH1A1 P00352 1/20 0.48
TSHR P16473 1/20 0.48
SLC6A2 P23975 1/20 0.44
TAAR1 Q96RJ0 1/20 0.44
KIF11 P52732 3/20 0.42
LMNA P02545 1/20 0.41
CYP2D6 P10635 1/20 0.41
KCNA5 P22460 1/20 0.41
CHRM1 P11229 3/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
HIF1A Q16665 1/20 0.40
CES1 P23141 1/20 0.40
CHRM4 P08173 1/20 0.40
CHRM5 P08912 1/20 0.40
ATM Q13315 1/20 0.39
CALM1 P0DP23 1/20 0.39
FDPS P14324 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30913969 0.82 KIF11 (0.45) CYP1A2CYP2C9CYP2C19TAAR1KIF11
SCHEMBL25008082 0.80 KIF11 (0.52) CYP1A2CYP2C9CYP2C19TAAR1KIF11
SCHEMBL4324787 0.78 ALDH1A1 (0.52) CYP1A2CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL30913981 0.76 KIF11 (0.49) CYP1A2CYP2C9CYP2C19TSHRKIF11
SCHEMBL9056088 0.76 CYP1A2 (0.50) CYP1A2CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL20654754 0.76 ALDH1A1 (0.44) CYP1A2CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL17940749 0.76 CYP1A2 (0.50) CYP1A2CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL16933828 0.76 SLC6A2 (0.42) CYP1A2CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL185769 0.76 SLC6A2 (0.50) CYP1A2CYP2C9CYP2C19ALDH1A1TSHR
SCHEMBL19224281 0.76 SLC6A2 (0.50) CYP1A2CYP2C9CYP2C19ALDH1A1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106920994-A A kind of Overcharge prevention electrolyte and lithium battery 张家港市国泰华荣化工新材料有限公司 2017-07-04 CN claimed
EP-3527600-B1 ISOCYANATE COMPOSITION AND PRODUCTION METHOD FOR ISOCYANATE POLYMER ASAHI CHEMICAL IND (JP) 2025-07-09 EP disclosed
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-04-13 US disclosed
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2023-01-10 US disclosed
CN-109803992-B Isocyanate composition and method for producing isocyanate polymer 旭化成株式会社 2022-05-24 CN disclosed
CN-109843963-B Isocyanate composition, method for producing isocyanate polymer, and isocyanate polymer 旭化成株式会社 2022-05-13 CN disclosed
EP-3536683-B1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2021-11-24 EP disclosed
US-11174337-B2 Isocyanate composition, method for producing isocyanate polymer and isocyanate polymer ASAHI KASEI KABUSHIKI KAISHA (JP) 2021-11-16 US disclosed
CN-107963982-B Polyisocyanate composition and isocyanate polymer composition 旭化成株式会社 2021-11-12 CN disclosed
EP-3372579-B1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION ASAHI CHEMICAL IND (JP) 2020-10-28 EP disclosed
US-10301417-B2 Polyisocyanate composition and isocyanate polymer composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2019-05-28 US disclosed
US-10125212-B2 Polyisocyanate composition and isocyanate polymer composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2018-11-13 US disclosed
EP-3372579-A1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION Asahi Kasei Kabushiki Kaisha (JP) 2018-09-12 EP disclosed
US-20170298169-A1 Polyisocyanate Composition and Isocyanate Polymer Composition ASAHI KASEI KABUSHIKI KAISHA (JP) 2017-10-19 US disclosed
CN-106920994-A A kind of Overcharge prevention electrolyte and lithium battery 张家港市国泰华荣化工新材料有限公司 2017-07-04 CN disclosed
EP-2915803-A1 POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION Asahi Kasei Chemicals Corporation (JP) 2015-09-09 EP disclosed
US-20150210631-A1 Polyisocyanate Composition and Isocyanate Polymer Composition ASAHI KASEI CHEMICALS CORPORATION (JP) 2015-07-30 US disclosed
US-20070265428-A1 HIGH PERFORMANCE POLYMER ELECTROLYTE WITH IMPROVED THERMAL AND CHEMICAL CHARACTERISTICS HOKU SCIENTIFIC, INC. - A DELAWARE CORP. (US) 2007-11-15 US disclosed
EP-1119535-A1 NOVEL BROMINE-CONTAINING 1,2-BIS(PHENYL)DIFLUOROMETHANES AND METHOD OF IMPARTING FLAME RETARDANCY TO FLAMMABLE MATERIALS Great Lakes Chemical Corporation (US) 2001-08-01 EP disclosed
WO-2000020364-A1 NOVEL BROMINE-CONTAINING 1,2-BIS(PHENYL)DIFLUOROMETHANES AND METHOD OF IMPARTING FLAME RETARDANCY TO FLAMMABLE MATERIALS GREAT LAKES CHEMICAL CORPORATION (US) 2000-04-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10301417-B2 Polyisocyanate composition and isocyanate polymer composition PAH, ALKBH1, ALKBH3 CYP1A2 60/4885CYP2C9 107/4885CYP2C19 507/4885
US-11548975-B2 Isocyanate composition and method for producing isocyanate polymer IDH3A, IDH2, IDH3B CYP1A2 195/4885CYP2C9 111/4885CYP2C19 638/4885
US-20170298169-A1 Polyisocyanate Composition and Isocyanate Polymer Composition TST, SUDS3, SCLY CYP1A2 520/4885CYP2C9 374/4885CYP2C19 1318/4885
US-20230114799-A1 ISOCYANATE COMPOSITION AND METHOD FOR PRODUCING ISOCYANATE POLYMER IDH3A, IDH2, IDH3B CYP1A2 183/4885CYP2C9 113/4885CYP2C19 639/4885
US-10125212-B2 Polyisocyanate composition and isocyanate polymer composition TST, SUDS3, SCLY CYP1A2 520/4885CYP2C9 374/4885CYP2C19 1318/4885
US-20150210631-A1 Polyisocyanate Composition and Isocyanate Polymer Composition TST, SUDS3, SCLY CYP1A2 520/4885CYP2C9 374/4885CYP2C19 1318/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.