Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | DRD4 | P21917 | 1/20 | 0.46 |
| ▸ | DRD3 | P35462 | 1/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.42 |
| ▸ | MAOA | P21397 | 2/20 | 0.42 |
| ▸ | MAOB | P27338 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7789152 | 0.84 | SIGMAR1 (0.53) | ALDH1A1LMNATSHRSIGMAR1 | |
| SCHEMBL7785087 | 0.84 | RAB9A (0.52) | MAOAMAOBRAB9AMTORGRM7 | |
| SCHEMBL1677375 | 0.79 | MTOR (0.65) | RAB9AMTORGRM7ALDH1A1LMNA | |
| SCHEMBL7785046 | 0.77 | TDP1 (0.49) | RAB9ANPC1ALDH1A1TSHRPOLB | |
| SCHEMBL17064544 | 0.76 | ALDH1A1 (0.56) | RAB9AMTORGRM7ALDH1A1LMNA | |
| SCHEMBL31067625 | 0.74 | MTOR (0.53) | MAOAMAOBRAB9AMTORGRM7 | |
| SCHEMBL17064829 | 0.74 | MTOR (0.53) | MAOAMAOBRAB9AMTORGRM7 | |
| SCHEMBL7787602 | 0.73 | ALDH1A1 (0.44) | MAOBALDH1A1LMNAMAPTCHRM1 | |
| SCHEMBL7780395 | 0.73 | MEN1 (0.42) | SLC6A4ALDH1A1SLC6A2 | |
| SCHEMBL27530411 | 0.72 | GRM8 (0.50) | RAB9ANPC1ALDH1A1TP53POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |