Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | MTOR | P42345 | 1/20 | 0.52 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.52 |
| ▸ | MAOA | P21397 | 4/20 | 0.51 |
| ▸ | MAOB | P27338 | 4/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7785046 | 0.88 | TDP1 (0.49) | RAB9ATSHRPRMT1SIGMAR1NPC1 | |
| SCHEMBL7616722 | 0.85 | RAB9A (0.71) | RAB9AMTORGRM7MAOAMAOB | |
| SCHEMBL7780393 | 0.84 | SLC6A3 (0.46) | RAB9AMTORGRM7MAOAMAOB | |
| SCHEMBL31067625 | 0.83 | MTOR (0.53) | RAB9AMTORGRM7MAOAMAOB | |
| SCHEMBL17064829 | 0.83 | MTOR (0.53) | RAB9AMTORGRM7MAOAMAOB | |
| SCHEMBL7789152 | 0.81 | SIGMAR1 (0.53) | TSHRSIGMAR1ALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17064544 | 0.79 | ALDH1A1 (0.56) | RAB9AMTORGRM7CYP3A4TSHR | |
| SCHEMBL17064881 | 0.78 | L3MBTL1 (0.49) | RAB9AMTORGRM7MAOAMAOB | |
| SCHEMBL31067567 | 0.78 | L3MBTL1 (0.49) | RAB9AMTORGRM7MAOAMAOB | |
| SCHEMBL10647657 | 0.76 | MAOA (0.43) | MAOAMAOBTSHRPRMT1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6329405-B1 | AS ILEAL BILE ACID TRANSPORTER INHIBITOR, FOR THERAPY OF HYPERLIPEMIA | SANKYO COMPANY, LIMITED (JP) | 2001-12-11 | — | — | US | disclosed |